lecture 4 Flashcards

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1
Q

aetiology

A

study of the causation/origination of a disorder

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2
Q

diathesis stress model

A

genetics and environment

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3
Q

heritability twin studies

A

37% for MDD

93% for bipolar disorder

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4
Q

2 polymorphisms related to vulnerability to develop MDD

A

polymorphism of the serotonin transporter gene and DRD4-2 gene- influence of dopamine

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5
Q

neurotransmitters initial assumption

A

absolute level of serotonin , dopamine in the synaptic cleft are associated with mood disorders either too high or low

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6
Q

depression is associated with

A

low dopamine and serotonin

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7
Q

mania is associated with

A

high dopamine and low serotonin

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8
Q

people with insensitive receptors experience

A

depressive symptoms as levels of serotonin drop

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9
Q

amygdala processes

A

emotions particularly fear- help assess how emotionally important a stimulus is

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10
Q

hippocampus what kind of activity for people with depression

A

diminished

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11
Q

overactivity in amygdala means

A

oversensitivity to emotionally relevant stimuli

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12
Q

hippocampus is related to

A

learning and memory

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13
Q

hpa axis does not seem to respond well to

A

biological signals to decrease cortisol levels

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14
Q

over secretion of cortisol results in

A

more people experiencing depressive symptoms

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15
Q

animal study evidence

A

cortisol levels high = depressive symptoms

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16
Q

social factors affecting depression

A

stressful life events, expressed emotion ,

17
Q

expressed emotion

A

family members critical/hostile comments towards the person with depression
high ee = relapse

18
Q

cognitive factor

A

becks negative triad- negative views of the self world and future

19
Q

hopelessness theory

A

expectation that a desirable outcome will not occur- expectation that one has no skills available to change the situation - locus of control

20
Q

rumination theory

A

tendency to ruminate- dwell on sad thoughts = increase risk of depression

21
Q

treatment approaches for MDD cognitive therapy

A

depression is caused by Negative schemas and cognitive biases

22
Q

what is cognitive therapys aim

A

alter maladaptive thought patterns

23
Q

behavioural activation therapy

A

caused by a lack of positive experiences - low levels of positive reinforcement

24
Q

aim of behavioural activation therapy

A

increase participation in positively reinforcing activities

25
Q

interpersonal therapy

A

due to the inability to communicate with others

26
Q

aim of interpersonal therapy

A

to identify major interpersonal problems and find solutions - one to one therapy

27
Q

behavioural couples therapy

A

caused by relationship problems - works to improve communication and relationship satisfaction

28
Q

biological treatment of mood disorders

A

medication and electroconvulsive therapy

29
Q

drugs

A

50-70% show major improvement but a strong placebo effect

30
Q

electroconvulsive therapy for depression

A

ECT is only used to treat people with MDD that have not responded to medication. 90% response rate but risk of short term confusion and memory loss

31
Q

combining treatment for MDD

A

psychotherapy and antidepressants - improve chances of recovery by more than 10-20% above either one treatment alone