lecture 2 Flashcards
hippocampus is a key
region in anterograde amnesia
damage to hippocampus results in
long term declarative memory formation impaired
korsakoffs syndrome
caused by thiamine deficiency as a result of long term alcohol abuse results in amnesia
amnesics are able to acquire
CR’s
eye blink conditioning experiement
subjects sat watching a movie whilst exposed to a tone then air puff
delay conditioning
who took part in the eye blink conditioning experiment
normal controls and a group of anterograde amnesics with hippocampal damage
results of eye blink conditioning
normal participants and amnesics acquired CR’S
but no amnesics formed a declarative memory of having undergone the procedure
but some normal controls did
not notice the CS-US relationship
trace conditioning
short beep then no stimulus then air puff
results of trace conditioning
amnesics failed to acquire CR’S
rat experiment
removal of hippocampus prior to conditioning - CR’S acquired if delay procedure is used but not the trace conditioning
what is needed for trace conditioning
hippocampus retains info about the CS over trace interval
if so- CR’s acquired before hippocampal removal should not be affected
stored memories are
not lost only the capacity to form new ones
hippocampus is crucial for
holding info overtime during acquisition of long term memories
hippocampus is Not involved in
delay conditioning but similar structure playing a similar role is the cerebral cortex
if the cerebella cortex is damaged
cr acquisition is no longer possible
If structures involved in acquisition are damaged
new long term memories cannot be stored - anterograde amnesia