Lecture 5 anatomy of heart Flashcards
Atrioventricular (AV) valves
incl function, right, left
Prevent blood returning to atria during ventricular
contraction.
tricuspid valve (3 leaflets)
bicuspid (mitral) valve (2 leaflets)
Semilunar valves (incl function, 2 types & cusps, Open & Close)
Prevent blood returning to the ventricle during filling (diastole).
Aortic (semilunar) valve (3 cusps)
Pulmonary (semilunar) valve (3 cusps)
Push open as blood flows out of heart.
close as blood starts to backflow.
Diastole -
valves open/closed
filling the ventricle.
AV opens,
ventricular chamber relaxed,
semilunar (outflow) valve are closed (caused by backflow towards ventricles).
Systole -
valves open/closed
Ventricles contract, AV close (to prevent back flow), pressure rises, semilunar valves opens (caused when pressure inside ventricular chamber exceeds pressure in outflow artery)
in systole what are the structures that keep the AV valve leaflet shut?
Papillary muscles (finger like projections of the myocardium that come of the wall point towards the valve leaflet)
Chordae tendinae (Attachment between papillary muscle and AV valve leaflet. heartstrings)
- Strong connective tissue can’t tear it.
- If pulled tear chordae tendernae from the papillary muscle.
2 arteries that supply the heart muscle
Right coronary artery - (groove from anterior to posterior)
Left coronary artery
First branches of the aorta / systemic circulation
Both arteries run in a groove between the atria and the ventricle (coronary groove)
Left coronary artery -
incl what does 2 branches it forms
thicker,
more blood supply,
more muscle,
runs short distance (left main stem), and
branches to form 2 branches an anterior branch (anterior interventricular artery) and the circumflex artery
anterior interventricular (coronary) artery -
runs over the interventricular system. Separates the 2 ventricular chambers.
branch forms from Left coronary artery
circumflex artery -
Runs in the left coronary groove around to the posterior of the heart.
branch forms from Left coronary artery
Venous drainage (cardiac vein) types
small cardiac vein (drains right side)
great cardiac vein (drains left side)
where do the cardiac veins end up?
in the same tubular structure (posterior of heart) called the coronary sinus
Cardiac muscle function
Beating of heart
- oxygen dependent metabolism
Cardiac Muscle Structure
made of, texture, structure, #nuclei, where nuclei is, where organelles are, how cells are connected
Isolated individual myocyte
Striated (like skeletal)
Short, fat, branched cell
1 - 2 nuclei / cell (like smooth)
Central (oval shaped) nuclei
Cytoplasmic organelles packed at poles of nuclei
Interconnected with
neighbouring cells via intercalated discs
Cardiomyocyte (sarcomeres)
how much volume of the cell does mitochondria make up?
20% of cytoplasm
Irregular branched sarcomeres (not like skeletal)
mitochondrial dependent metabolism
Aerobic oxygen dependent metabolism
Intercalated discs found where and consists of 3 junctions
only in Cardiac muscle
Adhesion belts (linking actin to actin) ~Vertical portion. - Physical propagation of contraction, generates alot of force that may pull the cells apart.
Desmosomes (linking cytokeratin with cytokeratin). (keep myocytes from pulling apart)
Gap junction (electrochemical communication) ~ Horizontal portion. Electrochemical propagation of contraction.