Lecture 16 Breathing / Ventilation Flashcards

1
Q

Boyle’s Law

A

P = 1 / V

inverse relationship between pressure and volume

decrease volume = increase pressure

increase volume = decrease pressure

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2
Q

Between breaths – pressure inside the thoracic cavity =

A
pressure outside (no pressure gradient in to out)
– No air movement
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3
Q

Change the pressure in one

A

air will move to lower pressure space

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4
Q

to breathe what do we need to establish to make air move?

A

pressure gradient

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5
Q

Changing the dimensions (volume) of the thorax, will change

A

pressure in the thorax, pressure in alveoli, and air will move

increase vol - air in
decrease vol - air out

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6
Q

Body Cavities

Pressure within a cavity

A

Change volume of the thorax
Change pressure
Greater or less than external air pressure
Air flows in or out

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7
Q

How is the volume of the thoracic cavity changed?

A

Boundaries of thorax

Movement of parts

  • muscles
  • joints
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8
Q

Thoracic cavity movement - pleura

what is Pleural fluid – thin film?

A

– Moist slippery surface – lung surface moves against other structures (diaphragm, thoracic wall)

– Holds lungs tight against thoracic wall – fluid bond between visceral and parietal pleura

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9
Q

thoracic wall movement results in lung movement

A
  • Increase volume of thorax
  • increase volume of lung
  • decrease pressure in lung
  • air flow in
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10
Q

Thoracic joints - anterior

A
  • Sternum to ribs
  • via costal cartilage (hyaline)
  • Synovial joints
  • Cartilaginous joints

sternocostal
costochondral
interchondral

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11
Q

Sternocostal

whats the joint?

A
  • Synovial

- Except 1st = cartilaginous

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12
Q

Costochondral

whats the joint?

A
  • cartilaginous
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13
Q

Interchondral

whats the joint?

A
  • synovial
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14
Q

Thoracic joints – posterior

A

costotransverse
vostovertebral

  • Articulation between thoracic vertebrae and ribs
  • Synovial joints = movement
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15
Q

Muscles of Respiration - inspiration

A
  • Diaphragm (main)
  • Intercostals
  • Accessory muscles
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16
Q

Quiet inspiration

A

active

• Diaphragm + external intercostals

17
Q

• Active inspiration

A
  • Add in accessory muscles

* Muscles which elevate ribs further

18
Q

Muscles of Respiration - expiration

A
  • Diaphragm
  • Intercostals
  • Accessory muscles (internal intercostal, abs)
19
Q

Quiet expiration

A

passive
• diaphragm + external
intercostals relax
• elastic tissue recoil

20
Q

• Active exhalation

A

Cough, if airway resistance is high, e.g. narrow airways in asthma

21
Q

Muscles of Respiration - expiration

Add in accessory muscles

A

– Muscles which reduce depth + width of thoracic cavity

– Abs muscles contract – decrease volume of abdominal cavity – push diaphragm up

22
Q

Inhalation –

A
volume increases (alveolar volume)
Pout > Pinside - air flows in
23
Q

Exhalation

A
volume decreases (alveolar volume)
Pout < Pinside - air flows out
24
Q

Summary: Breathing – thoracic volume changes

A

Contraction of diaphragm­ thoracic cavity length (75%)

Muscle (skeletal) - contract
Central tendon

25
Give one reason why you might develop a headache when you have a cold?
blocked sinuses
26
State the predominant type of respiratory epithelium in the nasal cavity?
pseudo stratified, ciliated columnar epithelium with goblet cells
27
What is the normal fate of mucus produced by this epithelium?
moved by cilia to pharynx and swallowed
28
Why does mucus accumulate in the respiratory tract of smokers?
cilia stop functioning due to damage from smoke inhalation
29
What cell type removes debris from the lungs?
macrophage