Lecture 27 - Bartonella Flashcards

1
Q

What are the structural characteristics of Bartonella?

A

Small, thin curved rods

Gram negative

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2
Q

What cell type for Bartonella have an affinity for?

A

Blood + Vascular endothelial cells

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3
Q

What type of pathogen is Bartonella?

A

Facultative intracellular pathogen

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4
Q

Which Bartonella is the only one not found worldwide? Where is it found?

A

B. Bacilliformis

South America

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5
Q

What are the three Bartonella we are concerned with?

A

Elizabethae
Vinsonii ssp. Berkoffii
Henselae

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6
Q

Species: Elizabethae

A

Rates

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7
Q

Species: Vinsonii ssp. Berkoffii

A

Dog

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8
Q

Species: Henselae

A

Cats

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9
Q

What carries the B. henselae bacteria?

A

Cat flea

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10
Q

What is the cat flea?

A

Ctenocephalides felis

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11
Q

What is the mechanism by which the B. Henselae is transferred from the flea to the cat?

A

Flea feces adhere to cat claws

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12
Q

What is the clincal presentation of B. Henselae in cats?

A

None

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13
Q

What are other two Bartonella, not including Henselae, that can cause Cat Scratch disease?

A

Clarridgeiae
– and –
Koehlerae

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14
Q

Where is CSD most common?

A

Tropical regions, does best in warmer climates

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15
Q

What causes cat scratch disease?

A

B. Henselae infect VES cells + Lymph nodes in humans

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16
Q

What can occur in people who are immunocompromised that are exposed to B. Henselae?

A

Bacteremia + Septicemia

17
Q

How long does it take chronic regional lymphadenopathy to occur?

A

3 to 50 day s

18
Q

How long does chronic regional lymphadenopathy stick around?

A

Months

19
Q

What can happen to LN in humans that are infected with B. Henselae?

A

Hyperplasia + Granuloma formation + Suppuration

20
Q

Which Bartonella causes bacillary angiomatosis?

A

B. henselae
– or –
B. Quintana

21
Q

What is the characteristics of bacillary angiomatosis when B. Henselae is responsible?

A

Involves:

Skin + Liver + Spleen + Lymph Nodes

22
Q

What is the characteristics of bacillary angiomatosis when B. Quintana is responsible?

A

Involves:

Skin + SQ + Bone

23
Q

What is used to stain Bartonella?

A

Warthin-starry silver stain

24
Q

What is the treatment for Bartonella?

A

Cat - doxycycline for 2 to 4 weeks