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Bacteriology > Lecture 19 - Campylobacter + Bordetella > Flashcards

Lecture 19 - Campylobacter + Bordetella Flashcards

1
Q

What are the two major characteristics based on the behavior of Campulobacter?

A

Commensal + Intracellular

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2
Q

Where is Campylobacter found?

A

GI and Gential tracts

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3
Q

What can an infection from Campylobacter cause?

A

Diarrhea + Abortion

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4
Q

What is special about the morphology of Camplyobacter?

A

Gull-winged

Spiral

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5
Q

Campylobacter: oxygen requirements

A

Micoaerophilic

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6
Q

What are the % of oxygen and CO2 that Campylobacter like?

A

5 to 10% O2

1 to 10% CO2

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7
Q

Campylobacter: oxidase

A

Positive

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8
Q

Campylobacter: catalase

A

varies

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9
Q

Campylobacter: MacConkey

A

Growth, w/ no fermentation (yellow)

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10
Q

What are the three Campylobacter strains that are responsible for verneral disease?

A

C. Fetus
C. Veneralis
C. Jejuni

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11
Q

Where do most Campylobacter outbreaks occur?

A

Western states

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12
Q

Which strain of Campylobacter is responsible for FBI’s in poultry?

A

C. Jejuni

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13
Q

What are the virulence factors that Camplyobacter contain?

A

Flagellar genes
Adhesins
Cytolehal distending toxin
S layer

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14
Q

What is another name for the S layer?

A

Microcapsule

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15
Q

What Campylobacter strains have an S layer?

A

C. Venerealis

C. Fetus

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16
Q

What is the general structure of the S layer?

A

Lattice

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17
Q

What does the S layer do?

A

Reduces susceptibility to pahgocytosis and complement

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18
Q

What is important about the S layer when it comes to chronic infections?

A

Has 8 different variants, allows for switching to keep hidden from the immune system

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19
Q

Which strains of Campylobacter has CDT?

A

C. Fetus

C. Jejuni

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20
Q

What does CDT cause?

A

Cell-cycle arrest
Distended host cell morphology
Leading to apoptosis

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21
Q

What does apoptosis via CDT allow for?

A

Releases bacteria within the cell

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22
Q

Where is C. vernrealis commonly found?

A

Bovine reproductive tract

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23
Q

What does C. venerealis cause?

A

Veneral disease in cattle
Early embryonic death
Infertility

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24
Q

Where does C. fetus commonly infect?

A

Intestinal tract of sheep, goats, and cattle

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25
Q

What does C. fetus tend to cause?

A

Abortion and stillbirths in sheep and goats
Weak offspring
Sporadic abortions in cattle

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26
Q

What does C. jejuni commonly infect?

A

Intestinal tract of birds and mammals

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27
Q

What does C. jejuni commonly cause in sheep?

A

Abortion

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28
Q

What does C. jejuni commonly cause in dogs?

A

Enteritis

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29
Q

What does C. jejuni commonly cause in birds?

A

Hepatitis

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30
Q

What disease process is caused by venerealis in cattle?

A

Bovine genital campylobacteriosis

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31
Q

What does Bovine genital campylobacteriosis cause in cattle?

A

Temporary infertility

Occasional abortion

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32
Q

What is the length on infection in bulls with C. venerealis?

A

Indefinite

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33
Q

Where does the infection spread in cattle in regards to C. venerealis?

A

uterus

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34
Q

How can C. Venerealis infect bulls indefinitely?

A

Antigenic SHIFT of S layer

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35
Q

What is the transmission route for C. Fetus?

A

Fecal - oral

36
Q

What does C. fetus cause in Birds?

A

Hepatitis

37
Q

What does C. fetus cause in cattle, pigs, and ewes?

A

Hemorrhagic enteritis + diarrhea

38
Q

What causes Ovine genital campylobacteriosis?

A

C. Fetus + C. Jejuni

39
Q

What are the symptoms of Ovine genital campylobacteriosis ?

A

Abortion

Necrotic placentitis

40
Q

What is the abortion pattern in ewes with Ovine genital campylobacteriosis?

A

Cyclical every 4 to 5 years

41
Q

Where does C. fetus localize in Ewes?

A

Uterus

42
Q

What disease process does C. Jejuni cause in birds?

A

Avian vibrionic hepatitis

43
Q

What are the symptoms of Avian vibrionic hepatitis?

A

Drop in egg production

Necrotic liver

44
Q

What causes canine intestinal campylobacteriosis?

A

C. Jejuni

45
Q

Whats a good way to note that Campylobacter may have been the cause of death in an aborted lamb?

A

Hepatic lesions

46
Q

What are the treatment methods for C. Fetus?

A

Therapeutic vaccination
Isolation
Antibiotics

47
Q

What is the AB used for C. Fetus?

A

Chlortetracycline

48
Q

What are the treatment methods for C. Jejuni?

A

Antibiotics

49
Q

What is the AB used for C. Jejuni?

A

Dihydrostreptomycin

50
Q

What are the treatment methods for C. Venerealis?

A

Antibiotics

51
Q

What is the AB used for C. Venerealis?

A

Dihydrostretomycin

52
Q

Where is bordetella a commensal bacteria?

A

URT of mammals and birds

53
Q

What does bordetella have an affinity for?

A

Ciliated respiratory epithelium

54
Q

What are the three major bordetella species?

A

Bronchospetica
Avium
Parapertussis

55
Q

Bordetella: oxygen requirements

A

Aerobic

56
Q

Bordetella: Gram

A

negative

57
Q

Bordetella: oxidase

A

positive

58
Q

Bordetella: Catalase

A

postive

59
Q

Bordetella: energy source

A

AA’s

60
Q

Bordetella: virulence factors

A

Adhesins

Toxins

61
Q

What types of adhesins does bordetella have?

A

Pertactin

Fimbriae

62
Q

What are the four toxins found in bordetella?

A

Tracheal cytotoxin
Dermonecrotoxin toxin
Osteotoxin
LPS

63
Q

What does the tracheal cytotoxin do?

A

Inhibits movement of cilia and tracheobronchial clearance

Can kill ciliated cells

64
Q

What symptom does tracheal cytotoxin cause?

A

Coughing

65
Q

What does dermonecrotoxic toxin cause?

A

Skin necrosis

Differentiation of osteoblasts

66
Q

What symptom does dermonecrotoxin cause?

A

Turbinate atrophy

67
Q

What does Osteotoxin cause?

A

Kills osteoblasts

68
Q

What three virulence factors are seen in B. Bronchoseptica?

A

Filamentous hemagglutinin
T3SS
Adenylate cyclase-hemolysin

69
Q

What animals are infected by B. parapertussis?

A

Lambs

70
Q

What does B. parapertussis cause in lambs?

A

Pneumonia

71
Q

B. Bronchispectica: Pigs

A

Atrophic rhinitis

72
Q

B. Bronchispectica: Dogs

A

Canine infectious tracheobronchitis

73
Q

B. Bronchispectica: Kittens

A

Pneumonia

74
Q

B. Bronchispectica: Horses

A

Respiratory infection

75
Q

B. Bronchispectica: rabbits

A

URI

76
Q

B. Bronchispectica: Lab rodents

A

Bronchopneumonia

77
Q

B. Avium: Turkeys

A

Coryza

78
Q

What commmon bacteria is a co-infection with Atrophic rhinitis?

A

Pasturella

79
Q

What are the symptoms of Kennel cough?

A

Coughing, retching, mild serous oculonasal discharge

80
Q

What are the symptoms of turkey coryza?

A

Beak breathing - Sneezing - Excesive lacrimation

81
Q

What is seen grossly in turkeys with B. Avium?

A

renal granulomas

flattened trachea

82
Q

What secondary infection occurs commonly in birds with B. Avium?

A

E. coli

83
Q

B. Bronchispectica: hemolysis

A

+

84
Q

B. Bronchispectica: urease

A

+

85
Q

B. avium + parapertussis: hemolysis

A

-

86
Q

B. avium + parapertussis: urease

A

-

Bacteriology (28 decks)

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