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Alimentory System > Inflamatory bowel disease > Flashcards

Inflamatory bowel disease Flashcards

1
Q

conditsion included in ibd

A

chrones, uc and microcpic oloitns

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2
Q

where does uc start and psread to

A

rectum and spreds proximmary but is contiane in colon

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3
Q

where is chones found

A

it is found in patches anywehre in the body,

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4
Q

what is when you have both uc and chrones

A

it is ibdu - unclaise inflatioary bowol disease

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5
Q

what is the two types of microscopci bowel disease

A

collangous colits and lympathcoic cytis

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6
Q

who is colangous colanits mainly seen in

A

females

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7
Q

what are the sympons of collangeous colonitis

A

belly pain
watery diharrea

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8
Q

cause of collangous colantis

A

inflatmo of the cell, reduice the absoaptonof water due to thicekn of eptilum

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9
Q

wha tis lympathic coltois

A

increas in lympathc cell

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10
Q

what is lympathc colotis asosiced with

A

meds such a sppi and ns aids
auto immune conditions such as rhmaoid artheris and celiac disease

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11
Q

symptons of lymphocytic colitis

A

dirahes and abdoal pain, simlar to collangeous colitis

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12
Q

treatmetn for lymphoticy colits

A

budenidies

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13
Q

does smokng increase risk for chones or uc

A

increase risk for chrones
reuces risk for UC

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14
Q

symptons of ibd

A

diahre, rectal bleeding, weight loss, fatique and abdomal pain

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15
Q

what bacteira are presnt in ibd more than in nroaml immenune system

A

acinobacteria and proteobacteria

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16
Q

what bacteira is presnet less in ibd

A

bacteroidets and lachnospiracease

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17
Q

what is the average age for uc

A

20 - 40

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18
Q

what is the symptson of uc

A

bloody diarrhoea
abdomal pain
weight loss
fatique

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19
Q

what area if inlfatin in procitis

A

rectum only

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20
Q

wjat area is inflatiend in procisgnitis

A

recutm and sigmoid col

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21
Q

what area is inflaed in left side colholits

A

all of hte left side of the colon

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22
Q

what area is inflated in pancolitis

A

whole colon

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23
Q

sympons of procitis

A

freqycl urgen, incotin an tenesums
blood
proxla faecl status constiapion

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24
Q

how to treat procitsi

A

topical therpaty

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25
Q

what is acute severe colitis

A

life threatening meidcial emercey with high mortaily of 2%`

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26
Q

scale of severity fo uc

A

mild less than 4 stools per day, with or with blood, normal esr, no sight of toxicity
moderate - 4- 6 stools per day, occasaioal blood, minla sings of toxicity , reduced crp
severe colitis , 6 or more blood stool, and any of , raised temp , tachycardia, anemai esr and raised crp
fulmainat - 10 stools per day, contius bleeding, toxicity k abdal tendersns or distion, tranfusion requice, colic dilation on x ray

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27
Q

bloods fuction in uc

A

inflamation marker, normocytic microcytic anemai
crp, wcc platlels, incrased
albumin reudced

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28
Q

stool test for uc

A

look for calprotecign and cultrue for incetion

29
Q

colonsocpy for uc

A

to look for maliganyc and polyops

30
Q

what is 1 and 2 on brisl tsotl tat

A

1 rabbit droping
2 - saus sheped byut lumps

31
Q

what is type 3, 4 and 5 on bristol stool chart

A

3 - sausage with cracks on surface
4 - sausag or smake and smoth and soft
5 - soft blobs with clear out edges

32
Q

what is 6 and 7 on bristol stool caht

A

6 - flffy pcies with ragged edge
7 ligquid

33
Q

tests for acute sever coloitsn in first 24 hours

A

blood tests
stool chart
4 cidf cultres

34
Q

drug tramtesn for first 24 hours for colitis

A

avoid / stop non sterold analgsi, opidaes, and dihrsl ant coholanse
iv glucocorticoids,
iv hydration

35
Q

what is the sympoosn of choroens disease

A

diharrheoa, abdomal pain, weight loss, malsais, lethary, anoxia, low grade fever, malabsobition, anemai, vi deifion

36
Q

blood for chornes

A

look for inflations

37
Q

stool for crones

A

to rule out infection if dihrar and fecla claproteicino

38
Q

what level of felauproic is normal, equivola nd elevated

A

0-50 nroal, 50 -200 equivol , greater than 200 raised

39
Q

what scan are done for crones

A

capusl endocpys, colonsocpy, mri small bowel stuy, occasional ct scan if acutly unwell

40
Q

what is the differen in histolgy bwtwen crones and uc

A

uc - goblet cell deped
greater cyrpa abcess
limited to mucoa

cd - tranmulra infalton
granumlomas

41
Q

what are some stucla complication ue to chroesn

A

inflation
sticure
fistula

42
Q

what is perianal choens disasesympons

A

unable to sit
pus secretion
perianal pain

43
Q

investigation for perianal crohns disease

A

mri pelvis
examion under anemaiths

44
Q

treatment for perianal choens

A

surgyer to drain it and put stent in place
medicaiton

45
Q

extrainteal manfiion of ibd

A

mot ulcer, skin / lesion, mucaion erthy nodum, pydodrl gancer, parim sclerous cholangitws

46
Q

cuase of choicn digrea

A

malabopoi e.g. pancreai inusigo or biel acid malabion, coleica diase, ibs, overflow diarra

47
Q

why does biel acid malbaion cause dihora

A

as bile acid is an laxative

48
Q

what are other diffencatno for ibd

A

ileocacel tb, coltiis, invfacein, amoberi, ishcmic

49
Q

who is most at risk fo rcolonic carcina

A

pancolits and those who have it for longest

50
Q

how oftne should low risk, medu risk and high risk people with adenocarino have colonsocpy from 10 years of onset of disease

A

low - 5, medium 3, high 1 year interval

51
Q

treatment pyimad of ibd

A

5 asa / sulfaszalide
predinsone or budensoid
immuno modulatrs
biologic gaens
surgery

52
Q

what is amiosaclicyates exampels

A

penseate which work on small bolw

53
Q

can 5asa be used in choesn

A

no , only effect in uc

54
Q

how can 5asa be used

A

orally dialy
during flairups
rectal topically

55
Q

who can recive steroid

A

both uc and cd

56
Q

common steroid

A

budesonid and prenosale

57
Q

what is required of rprenisole

A

calcium and vid d supplement

58
Q

what can metoterxate be used for

A

choesn only

59
Q

issue with methotreaat

A

it is a tetartogenic

60
Q

hwo qalify for methotrexate

A

steroid dependednt paitiens

61
Q

who can methoga be used on

A

crones only

62
Q

what are hte monc cona antiboids which can be used

A

infliximan - anti tnf alph antib
8 wekk iv infion

63
Q

new treatm for ibs

A

tonacinib, pan jak inahtor and is used orally

64
Q

how to give inflimab

A

8 weekly iv infuions

65
Q

what is the preiclp of elemtal feeding

A

feeding of only certain food snad othering else, non effecig in adults

66
Q

what is emergy cusry requied for ibd

A

acute sever colitis athat is not resond to high dose iv setoids
complatio such as perforation, absfes and fobsution

67
Q

what is the elective surgyer for in ibd

A

frequent relapse despite medical treatment
not able to tolerate medical treatment
steroid dependant
patient choice

68
Q

what is hte pouhc sueryg

A

wher the rmain reculaa stump can be use as a pouch to soer feauces

69
Q

wha is the downside of the pouch

A

it can lead to severla times per day need to go to toiled
can become infelcteld and inlfamed
can have obstions

Alimentory System (31 decks)

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