Alchol liver disease Flashcards
weekly recoomned units for men and women
14
is Gamma- glutamyl transpeptidase raised or lowered in liver disease
raised
time taken for alchol withdral syndomre after last drink
24 to 72 hours
symptoms of alchol withdrawl
Sweating
Tachycardia
Hypertension
Anxiety
Headache
Insomnia
Visual hallucinations
Weakness
Nausea
Retching
Vomiting
Seizures
what are benzodiazepine examples
diazepam, chlordiazepoxide or lorazepam
what drug treatment is needed for wirther of alchol
benzodiazepine and thipaine (b1)
is depression alsong encephglogctoy
yes
highest alchol morbity nation in uk
scotland
what is the intermedialy of alchol absobsiton
acetaldehyde
how is ethanol convred to acealdehyd
though nad, to nahd by alhcol dehydrogenase
or
nadph to nadp+ by cytochrome p4502e1
how s acetaldehyde turned to acetate
by nad, to nahd though acetaldehydae dehydrogenase
what is the dangeer alchol chemcial for liver
increased acetyldeh hydrate
and increas in nadh ration
what is steatotois
fatty liver disease
what is steatohepatisis
fatty liver with inflaiton
neurophiliic inflation
fibrosis, cirrhosis, build up of scar tissue
what is the cage questionalr for alchol
cut down alchol- ever felt need to
Annoyed - by someone cirtisied your during
guilty - about drinking
eyeopner - do you need one
how many units of alchol are in
a - glass of wine
b - shot
c - normal cider/ beer/ larger
d - bottle of wine
a - 2
b - 1
c- 2
d - 9
what score of fast is an immediate stop
3 or 4
first quetion on fast
having more than 6 units female or 8 unit male on single occasion
what are te cut off vales ofr the audio queson scoring for alchol
0-7 low risk
8-15 increasing risk
16-19 high risk
20+ possible dependence
signs of chroci liver diease on hands
leukonychima, dupuytens contracure, hepatic flap, clubbing, palmar erythema
general signs of alhcol liver disease
skin pigmentation
loss of hair
brusing
cachexia (muscle waisting)
what are the chest signs of alcholic liver disease
gynaemaosiam, breast atrophy, spider neuvid
what are the testiclar signs of alchol liver disea
atrophgy
what are the face signs of alcholic liver diseaw
jaunice, parotid gland enlargement
xanthelsma
what are the leg sings of chic liver diseas
scratch marks and odema
what ar teh abdomial signs of chrnic liver disease
asceites, hepatomelagly, dialted umbillac vessles , splenomegaly
what are the lab finds for alchol ilvier disease
aat >alt
rasied gamma glutamyl tranferase
macrocytosi
trhombocytopenia
what does gamma glucatml tranfaere indicate
liver or bile duct damage
what are the 4 grades of hepatic encephalopathy
1- mild confusion
4- comatosed
caues of hepatic encepholoapgy
infection, drugs, constiapation, gi bleed, electorlyte distubance
what are alternative diagnos for hepatic encephaolpathy
infecton, hyypoglycaemia, intracrainal bleed
treatment fo hepatic encephalogpy
bowwl clear out, laculsoe, enema, antibioci, itu, airway suppor, ng tube for meds
what are the symptons of sponateus bacterial peritoneis
abdomal pain, fevour , rigos, renal imparime , sepsi, tahcaria, temp
why do you tap sponatsu bacterial peritonitis
fluid prion adn glucose levles
cutlres
white cell count
treatment for spontaous bactial periotnais
iv antibioc
ascitic fluid drin
iv albumin infusion
what is acute bactieal periotnsi
acute infeiction of asciteis
presntaion of alcholic hepatis
jauicne, encephalopathy, infection, decopais hepatic fucniton
sings of decomapti hepatic fucton
low albumin and rised prothorbin time
change in biochemcial in alhcol hepatis
raised bilirubin, riased ggt and alkp
treatme for alcholic hepatis
supportive
treat encepaholy
trat alchol withdraw
protect against gi bleed
protect airway
tratme fo ralchol withde
bendodiapiens
what grade on the galsgow alcholidd hepatisi score do you need for sternodi to be worth it
9 or hgiher
what grade do you need to be on maddrey discriment fucniton to treat with oral steroids
32
how to offer ntuion for alcoli hepatis
ng tube with high nution frequent feeds
benfiit of nutrion in alhcolhepis
changes 2 year survi form 15% to 70%
what are the cause of fatty liver diseae
obesity
diabes
hypercholsia
signs of steathopais
raised alanine amio transfase
fatty fliver on uss
