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Alimentory System > Alchol liver disease > Flashcards

Alchol liver disease Flashcards

1
Q

weekly recoomned units for men and women

A

14

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2
Q

is Gamma- glutamyl transpeptidase raised or lowered in liver disease

A

raised

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3
Q

time taken for alchol withdral syndomre after last drink

A

24 to 72 hours

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4
Q

symptoms of alchol withdrawl

A

Sweating
Tachycardia
Hypertension
Anxiety
Headache
Insomnia
Visual hallucinations
Weakness
Nausea
Retching
Vomiting
Seizures

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5
Q

what are benzodiazepine examples

A

diazepam, chlordiazepoxide or lorazepam

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6
Q

what drug treatment is needed for wirther of alchol

A

benzodiazepine and thipaine (b1)

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7
Q

is depression alsong encephglogctoy

A

yes

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8
Q

highest alchol morbity nation in uk

A

scotland

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9
Q

what is the intermedialy of alchol absobsiton

A

acetaldehyde

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10
Q

how is ethanol convred to acealdehyd

A

though nad, to nahd by alhcol dehydrogenase
or
nadph to nadp+ by cytochrome p4502e1

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11
Q

how s acetaldehyde turned to acetate

A

by nad, to nahd though acetaldehydae dehydrogenase

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12
Q

what is the dangeer alchol chemcial for liver

A

increased acetyldeh hydrate
and increas in nadh ration

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13
Q

what is steatotois

A

fatty liver disease

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14
Q

what is steatohepatisis

A

fatty liver with inflaiton
neurophiliic inflation
fibrosis, cirrhosis, build up of scar tissue

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15
Q

what is the cage questionalr for alchol

A

cut down alchol- ever felt need to
Annoyed - by someone cirtisied your during
guilty - about drinking
eyeopner - do you need one

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16
Q

how many units of alchol are in
a - glass of wine
b - shot
c - normal cider/ beer/ larger
d - bottle of wine

A

a - 2
b - 1
c- 2
d - 9

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17
Q

what score of fast is an immediate stop

A

3 or 4

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18
Q

first quetion on fast

A

having more than 6 units female or 8 unit male on single occasion

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19
Q

what are te cut off vales ofr the audio queson scoring for alchol

A

0-7 low risk
8-15 increasing risk
16-19 high risk
20+ possible dependence

20
Q

signs of chroci liver diease on hands

A

leukonychima, dupuytens contracure, hepatic flap, clubbing, palmar erythema

21
Q

general signs of alhcol liver disease

A

skin pigmentation
loss of hair
brusing
cachexia (muscle waisting)

22
Q

what are the chest signs of alcholic liver disease

A

gynaemaosiam, breast atrophy, spider neuvid

23
Q

what are the testiclar signs of alchol liver disea

A

atrophgy

24
Q

what are the face signs of alcholic liver diseaw

A

jaunice, parotid gland enlargement
xanthelsma

25
Q

what are the leg sings of chic liver diseas

A

scratch marks and odema

26
Q

what ar teh abdomial signs of chrnic liver disease

A

asceites, hepatomelagly, dialted umbillac vessles , splenomegaly

27
Q

what are the lab finds for alchol ilvier disease

A

aat >alt
rasied gamma glutamyl tranferase
macrocytosi
trhombocytopenia

28
Q

what does gamma glucatml tranfaere indicate

A

liver or bile duct damage

29
Q

what are the 4 grades of hepatic encephalopathy

A

1- mild confusion
4- comatosed

30
Q

caues of hepatic encepholoapgy

A

infection, drugs, constiapation, gi bleed, electorlyte distubance

31
Q

what are alternative diagnos for hepatic encephaolpathy

A

infecton, hyypoglycaemia, intracrainal bleed

32
Q

treatment fo hepatic encephalogpy

A

bowwl clear out, laculsoe, enema, antibioci, itu, airway suppor, ng tube for meds

33
Q

what are the symptons of sponateus bacterial peritoneis

A

abdomal pain, fevour , rigos, renal imparime , sepsi, tahcaria, temp

34
Q

why do you tap sponatsu bacterial peritonitis

A

fluid prion adn glucose levles
cutlres
white cell count

35
Q

treatment for spontaous bactial periotnais

A

iv antibioc
ascitic fluid drin
iv albumin infusion

36
Q

what is acute bactieal periotnsi

A

acute infeiction of asciteis

37
Q

presntaion of alcholic hepatis

A

jauicne, encephalopathy, infection, decopais hepatic fucniton

38
Q

sings of decomapti hepatic fucton

A

low albumin and rised prothorbin time

39
Q

change in biochemcial in alhcol hepatis

A

raised bilirubin, riased ggt and alkp

40
Q

treatme for alcholic hepatis

A

supportive
treat encepaholy
trat alchol withdraw
protect against gi bleed
protect airway

41
Q

tratme fo ralchol withde

A

bendodiapiens

42
Q

what grade on the galsgow alcholidd hepatisi score do you need for sternodi to be worth it

A

9 or hgiher

43
Q

what grade do you need to be on maddrey discriment fucniton to treat with oral steroids

A

32

44
Q

how to offer ntuion for alcoli hepatis

A

ng tube with high nution frequent feeds

45
Q

benfiit of nutrion in alhcolhepis

A

changes 2 year survi form 15% to 70%

46
Q

what are the cause of fatty liver diseae

A

obesity
diabes
hypercholsia

47
Q

signs of steathopais

A

raised alanine amio transfase
fatty fliver on uss

Alimentory System (31 decks)

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