Immunology: Vaccination Flashcards

1
Q

Vaccination:

Outline the schedule of childhood vaccination

A
  • D = Diphtheria
  • T = Tetanus
  • aP = acellular Pertussis (whooping cough)
  • IPV = Inactivated Polio
  • HiB = Haemophilus influenza type b
  • MMR = Measles, mumps
  • rubella PCV = Pneumococcal conjugate vaccine
  • Men C = Meningitis C
  • R = rotavirus gastroenteritis (oral)
  • HPV = Human papilloma virus type 16,18 (3 injections at 1,3,6 months)
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2
Q

Vaccination:

Who are at risk individuals?

What vaccines do they need?

A
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3
Q

Vaccination:

  • Who are at risk groups?
  • Which Vaccinations are needed for travel?
  • Who needs the BCG? Who needs T/IP vaccine?
  • Who needs DTaP/IPV vaccine?
  • Who needs Shingles vaccine?
A
  • 65 and over
  • Cholera, Hep A, Hep BT, Tick-borne encephalopathy, Typhoid, Yellow Fever
  • BCG = All at risk infants
  • T/IPV = if not immunised child
  • DTaP/IPV - pregnant women 28 to 38 weeks gestation
  • Shingles = 70 to 79 year olds
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4
Q

Vaccination:

What is the progression of antibody concentration in first and second exposures?

A
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5
Q

Vaccination:

What does vaccination rely on?

A
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6
Q

Vaccination:

What is herd immunity?

A
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7
Q

Vaccination:

What are Antigen Presenting Cells (APCs)?

A
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8
Q

Vaccination:

What are the locations, antigens, cytokines and memory types of Central and Effector memory cells?

A
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9
Q

Vaccination:

What do CCR7, CCL19, CCL21 and CD62L do?

A
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10
Q

Vaccination:

What antigens do T Memory cells have and what do they bind to?

A
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11
Q

Vaccination:

What are the features of B Memory Cells?

A
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12
Q

Vaccination:

Outline the T helper cell response

A
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13
Q

Vaccination:

What are the features of the perfect vaccination?

A

1

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14
Q

Vaccination:

What is the progression of a vaccine?

A
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15
Q

Vaccination:

What are the different routes of admission of vaccines?

A
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16
Q

Vaccination:

Which cells mediate the response to Influenza and TB vaccines?

A
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17
Q

Vaccination:

What are the ways to ensure a good response to generate effective memory?

A
18
Q

Vaccination:

What are the Cancer Vaccines?

A
19
Q

Vaccination:

What are the Alzheimer’s disease Vaccines?

A
20
Q

Vaccination:

Why don’t vaccinations work effectively in the elderly?

A
21
Q

Vaccination:

What are the indications for bone marrow transplantation?

A
22
Q

Types of Vaccine:

What are the advantages of live vaccines?

A
23
Q

Types of Vaccine:

What are the disadvantages of live vaccines?

A
24
Q

Types of Vaccine:

What are the examples of live vaccines?

A
25
Q

Types of Vaccine:

What are the advantages of inactivated vaccines?

A
26
Q

Types of Vaccine:

What are the disadvantages of inactivated vaccines?

A
27
Q

Types of Vaccine:

What are the examples of inactivated vaccines?

A
28
Q

Types of Vaccine:

What is the definition of a DNA vaccine?

A
29
Q

Types of Vaccine:

What are the advantages of DNA vaccines?

A
30
Q

Types of Vaccine:

What are the disadvantages of DNA vaccines?

A
31
Q

Types of Vaccine:

What are the examples of DNA vaccines?

A
32
Q

Types of Vaccine:

What types of vaccines can HIV patients not have and which ones are okay?

A
33
Q

Vaccination:

What is the definition of a Vaccine Adjutant?

A
34
Q

Vaccination:

What is the action of Depot adjuvant?

A
35
Q

Vaccination:

What is the action of ALUM adjuvant?

A
36
Q

Vaccination:

What is the action of CpG adjuvant?

A
37
Q

Vaccination:

What is the action of Complete Freund’s adjuvant?

A
38
Q

Vaccination:

What is the action of ISCOMS (Immune Stimulating Complex) adjuvant?

A
39
Q

Vaccination:

What is the action of Interleukin 2 adjuvant?

A
40
Q

Vaccination:

What are the passive vaccines?

A
41
Q

Vaccination:

What is the Mantoux test?

A