Immunology: HIV

Question 1

Pathogenesis:

What is the very basic aetiology of HIV?

Answer 1

Question 2

Epidemiology:

How many people are living with HIV and how many have died from AIDS?

Answer 2

Question 3

Epidemiology:

How many people are infected with HIV each day?

Answer 3

Question 4

Epidemiology:

How is HIV transmitted and how does it gain entry to cells?

Answer 4

Question 5

Pathogenesis:

What is the innate response to HIV?

Answer 5

Question 6

Pathogenesis:

What is the adaptive response to HIV?

Answer 6

Question 7

Pathogenesis:

How does HIV damage the immune response?

Answer 7

Question 8

Life cycle:

What is the life cycle of HIV?

Answer 8

Question 9

Natural history:

What is the natural history of HIV?

Answer 9

Question 10

Natural history:

Outline the changes in Mucosal CD4 T cells, CD4 T cell counts in blood, Viremia and Immune activation in HIV over weeks, years and months.

Answer 10

Question 11

Diagnosis:

What is the screening test and confirmation test for HIV?

Answer 11

Question 12

Diagnosis:

What investigations happen after diagnosis?

Answer 12

Question 13

Treatment:

What is the current treatment of HIV?

Answer 13

Question 14

Treatment:

What is HIV treatment in Pregnancy?

Answer 14

(Also called AZT, an NRTI that acts as a Thymidine analogue)

Question 15

Treatment:

What are the limitations of HAART?

Answer 15

Question 16

Treatment:

Outline the treatment diagram for HIV

Answer 16

Question 17

HIV Treatment:

What are the examples and side effects of Fusion inhibitors?

Answer 17

Question 18

HIV Treatment:

What are the examples and side effects of Attachment inhibitors?

Answer 18

Question 19

HIV Treatment:

What are the examples and side effects of Nucleoside Reverse Transcriptase inhibitors (NRTI)?

Answer 19

“DAZZLES TEC”

• Didanosine
• Abacavir
• Zalcitabine
• Zidovudine
• Lamivudine
• Emtricitabine
• Stavudine
• Trizivir
• Epzicom
• Combivir

Question 20

HIV Treatment:

What are the examples and side effects of Non-NRTI?

Answer 20

Question 21

HIV Treatment:

What are the examples and side effects of Integration inhibitors?

Answer 21

Question 22

HIV Treatment:

What are the examples and side effects of Protease inhibitors?

Answer 22

“FINALS RA”

• Fosampernavir
• Indinavir
• Nelfinavir
• Amprenavir
• Lopinavir
• Saquinavir
• Ritonavir
• Amprenavir

Question 23

HIV Treatment:

What are the examples and side effects of Nucleotide RTI?

Answer 23