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Year 5 - Krish Pathology Guide 2018 > Immunology: Transplantation > Flashcards

Immunology: Transplantation Flashcards

1
Q

Transplantation:

What is transplantation rejection and what are its stages?

A
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2
Q

Transplantation:

Outline the process of immune recognition

A
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3
Q

Transplantation:

What are the antigens recognised following transplant?

A
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4
Q

Transplantation:

What are the 2 types of recognition in transplant?

A
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5
Q

Activation and Effector Function:

What is activation and effector function?

A
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6
Q

Activation and Effector Function:

What are the phases of immune response to transplant?

A
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7
Q

Activation and Effector Function:

What is the T Cell function in transplant rejection?

A
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8
Q

Activation and Effector Function:

What is acute vascular rejection?

A
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9
Q

Activation and Effector Function - Types of Transplant Rejection:

What is the time, mechanism pathology and treatment for Hyperacute Rejection?

A
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10
Q

Activation and Effector Function - Types of Transplant Rejection:

What is the time, mechanism pathology and treatment for Acute-Cellular Rejection?

A
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11
Q

Activation and Effector Function - Types of Transplant Rejection:

What is the time, mechanism pathology and treatment for Acute- Antibody Mediated Rejection?

A
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12
Q

Activation and Effector Function - Types of Transplant Rejection:

What is the time, mechanism pathology and treatment for Chronic Rejection?

A
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13
Q

Activation and Effector Function - Types of Transplant Rejection:

What is the time, mechanism pathology and treatment for Graft versus Host Disease (GvHD)?

A
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14
Q

Matching:

How are antigenic differences between donors and recipients reduced?

A
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15
Q

Matching:

What immune agents are given before a transplant?

A

OKT3 = Muromonab

ATG = anti-thymocyte globulin

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16
Q

Matching:

What immune agents are given after transplant and give some examples?

A

CNI= Calcinurin inhibitor

MMF = Mycophenolic acid

Aza = Azathioprine

17
Q

Matching:

What are used to treat episodes of acute transplant rejection?

A

OKT3 = Muromonab

ATG = anti-thymocyte globulin

18
Q

Haemopoietic stem cell transplantation (HSCT):

Outline the aetiology, symptoms and treatment of Haemopoietic stem cell transplantation (HSCT)

19
Q

Haemopoietic stem cell transplantation (HSCT):

What is an isograft, allograft, xenograft and split graft?

20
Q

Haemopoietic stem cell transplantation (HSCT):

What are the infection related post transplant complications?

21
Q

Haemopoietic stem cell transplantation (HSCT):

What are the malignancy related post transplant complications?

22
Q

Haemopoietic stem cell transplantation (HSCT):

What are the Cardiovascular related post transplant complications?

23
Q

Haemopoietic stem cell transplantation (HSCT):

What are the sources of Allografts?

Year 5 - Krish Pathology Guide 2018 (70 decks)

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