Immunology: Immune Therapies Flashcards

1
Q

Boosting immune response:

Outline the broad classification of Immune Modulation therapies

A
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2
Q

Boosting immune response:

Outline the features of Human Normal Immunoglobulin therapy

A
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3
Q

Boosting immune response:

Outline the features of Specific Immunoglobulin

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4
Q

Boosting immune response:

Outline the features of Recombinant Cytokines

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5
Q

Boosting immune response:

Outline the features of Blocking immune checkpoints

A
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6
Q

Immunosuppressive therapies:

Outline the features of injection site reactions

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7
Q

Immunosuppressive therapies:

Outline the features of infusion reactions

A
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8
Q

Immunosuppressive therapies:

Outline the types of immunosuppressive therapies (visually)

A
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9
Q

Immunosuppressive therapies:

Outline the process of Allergen Desensitization

A
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10
Q

Immunosuppressant Drugs:

What are the main types of immunosuppressant drugs?

A
  • Corticosteriods:
    • Prednisolone
  • Antiproliferative Agents: “CAMM”
    • ​Cyclophosphamide
    • Azathioprine
    • Myclophosphamide
    • Methotrexate
  • Plasmapheresis
  • Inhibitors of cell signalling: “TTACS”
    • ​Tacrolimus
    • Tofacinib
    • Apremilast
    • Cyclosporin
    • Sirolimus
  • Agents directed at cell surface antigens: “ADAMANT BER”
    • Abatacept
    • Daclizumab
    • Anti thymocyte
    • Muromonab CD3
    • Alemtuzumab
    • Natalizumab
    • Tocilizumab
    • ​Basiliximab
    • Efalizumab
    • Rituximab
  • Agents directed at cytokines “GAUDIES C”:
    • Golimumab
    • Adalimumab
    • Ustekinumab
    • Denosumab
    • ​Infliximab
    • Etanercept
    • Secukinumab
    • Certolizumab
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11
Q

Immunosuppressant Drugs:

What is the mode of action for Prednisolone?

A
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12
Q

Immunosuppressant Drugs:

What are the indications for Prednisolone?

A
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13
Q

Immunosuppressant Drugs:

What are the side effects of Prednisolone?

A

Essentially Cushing’s Symptoms

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14
Q

Immunosuppressant Drugs:

What is the mode of action for Cyclophosphamide?

A
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15
Q

Immunosuppressant Drugs:

What are the indications for Cyclophosphamide?

A
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16
Q

Immunosuppressant Drugs:

What are the side effects of Cyclophosphamide?

A
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17
Q

Immunosuppressant Drugs:

What is the mode of action for Mycophenolate Mofetil?

A
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18
Q

Immunosuppressant Drugs:

What are the indication for Mycophenolate Mofetil?

A
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19
Q

Immunosuppressant Drugs:

What are the side effects of Mycophenolate Mofetil?

A
20
Q

Immunosuppressant Drugs:

What is the mode of action for Azathioprine?

A
21
Q

Immunosuppressant Drugs:

What are the indications for Azathioprine?

A
22
Q

Immunosuppressant Drugs:

What are the side effects of Azathioprine?

A
23
Q

Immunosuppressant Drugs:

What is the mode of action for Methotrexate?

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24
Q

Immunosuppressant Drugs:

What are the indications for Methotrexate?

A
25
Q

Immunosuppressant Drugs:

What are the side effects of Methotrexate?

A
26
Q

Immunosuppressant Drugs:

What is the mode of action for Plasmapheresis?

A
27
Q

Immunosuppressant Drugs:

What are the indications for Plasmapheresis?

A
28
Q

Immunosuppressant Drugs:

What are the side effects of Plasmapheresis?

A
29
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Tacrolimus and Cyclosporine?

A
30
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Sirolimus, Tofacitinib and Apremilast?

A
31
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Basiliximab?

A
32
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Abatacept?

A
33
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Rituximab?

A
34
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Natalizumab?

A
35
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Tocilizumab?

A
36
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Muromonab-CD3?

A
37
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Anti-thymocyte globulin (ATG)?

A
38
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Daclizumab?

A
39
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Efalizumab?

A
40
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Infliximab, Adalimumab, Certolizumab and Golimumab?

A
41
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Etanercept?

A
42
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Ustekinumab?

A
43
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Secukinumab?

A
44
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Denosumab?

A
45
Q

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Alemetuzumab?

A