Immunology: Immune Therapies

Question 1

Boosting immune response:

Outline the broad classification of Immune Modulation therapies

Answer 1

Question 2

Boosting immune response:

Outline the features of Human Normal Immunoglobulin therapy

Answer 2

Question 3

Boosting immune response:

Outline the features of Specific Immunoglobulin

Answer 3

Question 4

Boosting immune response:

Outline the features of Recombinant Cytokines

Answer 4

Question 5

Boosting immune response:

Outline the features of Blocking immune checkpoints

Answer 5

Question 6

Immunosuppressive therapies:

Outline the features of injection site reactions

Answer 6

Question 7

Immunosuppressive therapies:

Outline the features of infusion reactions

Answer 7

Question 8

Immunosuppressive therapies:

Outline the types of immunosuppressive therapies (visually)

Answer 8

Question 9

Immunosuppressive therapies:

Outline the process of Allergen Desensitization

Answer 9

Question 10

Immunosuppressant Drugs:

What are the main types of immunosuppressant drugs?

Answer 10

• Corticosteriods:
  
  • ​Prednisolone
• Antiproliferative Agents: “CAMM”
  
  • ​Cyclophosphamide
  • Azathioprine
  • Myclophosphamide
  • Methotrexate
• Plasmapheresis
• Inhibitors of cell signalling: “TTACS”
  
  • ​Tacrolimus
  • Tofacinib
  • Apremilast
  • Cyclosporin
  • Sirolimus
• Agents directed at cell surface antigens: “ADAMANT BER”
  
  • Abatacept
  • Daclizumab
  • Anti thymocyte
  • Muromonab CD3
  • Alemtuzumab
  • Natalizumab
  • Tocilizumab
  • ​Basiliximab
  • Efalizumab
  • Rituximab
• Agents directed at cytokines “GAUDIES C”:
  
  • Golimumab
  • Adalimumab
  • Ustekinumab
  • Denosumab
  • ​Infliximab
  • Etanercept
  • Secukinumab
  • Certolizumab

Question 11

Immunosuppressant Drugs:

What is the mode of action for Prednisolone?

Answer 11

Question 12

Immunosuppressant Drugs:

What are the indications for Prednisolone?

Answer 12

Question 13

Immunosuppressant Drugs:

What are the side effects of Prednisolone?

Answer 13

Essentially Cushing’s Symptoms

Question 14

Immunosuppressant Drugs:

What is the mode of action for Cyclophosphamide?

Answer 14

Question 15

Immunosuppressant Drugs:

What are the indications for Cyclophosphamide?

Answer 15

Question 16

Immunosuppressant Drugs:

What are the side effects of Cyclophosphamide?

Answer 16

Question 17

Immunosuppressant Drugs:

What is the mode of action for Mycophenolate Mofetil?

Answer 17

Question 18

Immunosuppressant Drugs:

What are the indication for Mycophenolate Mofetil?

Answer 18

Question 19

Immunosuppressant Drugs:

What are the side effects of Mycophenolate Mofetil?

Answer 19

Question 20

Immunosuppressant Drugs:

What is the mode of action for Azathioprine?

Answer 20

Question 21

Immunosuppressant Drugs:

What are the indications for Azathioprine?

Answer 21

Question 22

Immunosuppressant Drugs:

What are the side effects of Azathioprine?

Answer 22

Question 23

Immunosuppressant Drugs:

What is the mode of action for Methotrexate?

Answer 23

Question 24

Immunosuppressant Drugs:

What are the indications for Methotrexate?

Answer 24

Question 25

Immunosuppressant Drugs:

What are the side effects of Methotrexate?

Answer 25

Question 26

Immunosuppressant Drugs:

What is the mode of action for Plasmapheresis?

Answer 26

Question 27

Immunosuppressant Drugs:

What are the indications for Plasmapheresis?

Answer 27

Question 28

Immunosuppressant Drugs:

What are the side effects of Plasmapheresis?

Answer 28

Question 29

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Tacrolimus and Cyclosporine?

Answer 29

Question 30

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Sirolimus, Tofacitinib and Apremilast?

Answer 30

Question 31

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Basiliximab?

Answer 31

Question 32

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Abatacept?

Answer 32

Question 33

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Rituximab?

Answer 33

Question 34

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Natalizumab?

Answer 34

Question 35

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Tocilizumab?

Answer 35

Question 36

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Muromonab-CD3?

Answer 36

Question 37

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Anti-thymocyte globulin (ATG)?

Answer 37

Question 38

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Daclizumab?

Answer 38

Question 39

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Efalizumab?

Answer 39

Question 40

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Infliximab, Adalimumab, Certolizumab and Golimumab?

Answer 40

Question 41

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Etanercept?

Answer 41

Question 42

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Ustekinumab?

Answer 42

Question 43

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Secukinumab?

Answer 43

Question 44

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Denosumab?

Answer 44

Question 45

Immunosuppressant Drugs:

What is/are the mode of action, indications and side effects of Alemetuzumab?

Answer 45