Histopathology: Liver Pathology

Question 1

Liver Pathology:

What is the basic structure of the Liver?

Answer 1

Question 2

Liver Pathology:

What are centrilobular and Periportal hepatocytes?

Answer 2

Question 3

Liver Pathology:

What are the main functions of the liver?

Answer 3

Question 4

Liver Pathology:

What is/are the definition and main features of Cirrhosis?

Answer 4

Question 5

Liver Pathology:

What are the main causes of Cirrhosis?

Answer 5

Question 6

Liver Pathology:

How can Cirrhosis be classified?

Answer 6

Question 7

Liver Pathology:

What is the pathophysiology of Cirrhosis?

Answer 7

Question 8

Liver Pathology:

What are the implications of different Child Pugh scores?

Answer 8

Question 9

Liver Pathology:

What is the definition of Portal Hypertension?

What is it secondary to?

Answer 9

Question 10

Liver Pathology:

What happens when portal pressure exceeds 10 to 12 mmHg?

Answer 10

Question 11

Liver Pathology:

What are the causes of Portal Hypertension?

Answer 11

Question 12

Liver Pathology:

What are the causes of Cirrhosis?

Answer 12

• Alcoholic liver disease
  
  • Alcoholic hepatitis
  • Hepatic steatosis
  • Alcoholic Cirrhosis
• Non Alcoholic Fatty Liver Disease
  
  • ​Simple steatosis
  • Non-Alcoholic fatty liver disease
• Viral Hepatitis
• Autoimmune hepatitis
  
  • Type 1
  • Type 2
• Biliary causes of cirrhosis
  
  • Primary biliary cirrhosis
  • Primary Sclerosing cholangitis

Question 13

Liver Pathology:

What is/are the definition and subtypes of Non Alcoholic Fatty Liver disease?

Answer 13

Question 14

Liver Pathology:

What is/are the epidemiology, genetics, subtypes and treatment of Autoimmune Hepatitis?

Answer 14

Question 15

Liver Pathology:

What is/are the definition, epidemiology, and investigations of Primary Biliary Cirrhosis (PBC)?

Answer 15

Question 16

Liver Pathology:

What is/ are the histology, symptoms and treatment of Primary Biliary Cirrhosis (PBC)?

Answer 16

Question 17

Liver Pathology:

What is/are the definition and epidemiology of Primary Sclerosing Cholangitis (PSC)?

Answer 17

Question 18

Liver Pathology:

What are the investigations for Primary Sclerosing Cholangitis (PSC)?

Answer 18

Question 19

Liver Tumours:

What is the classification of liver tumours?

Answer 19

• Benign
  
  • Hepatic adenoma
  • Haemangioma
• Malignant
  
  • Hepatocellular
  • Carcinoma
  • Angiosarcoma
  • Hepatoblastoma
  • Cholangiosarcoma
  • Metastasis from other primary sources

Question 20

Liver Tumours:

What are the clinical features of Hepatic adenoma?

Answer 20

Question 21

Liver Tumours:

What are the clinical features of Haemangioma?

Answer 21

Question 22

Liver Tumours:

What are the clinical features of Hepatocellular Carcinoma?

Answer 22

Question 23

Liver Tumours:

What are the clinical features of Cholangiocarcinoma?

Answer 23

Question 24

Liver Tumours:

What are the clinical features of Metastases from other primary tumours?

Answer 24

Question 25

Modified Child Pugh Score:

What is the score of 1, score of 2 and score of 3 for:

1. Ascites
2. Encephalopathy
3. Bilirubin
4. Albumin
5. Prothrombin time (sec > normal).

Answer 25

Question 26

Alcoholic Liver Disease:

What are the macroscopic and microscopic characteristics of Hepatic Steatosis (Fatty Liver)?

Answer 26

Question 27

Alcoholic Liver Disease:

What are the macroscopic and microscopic characteristics of Alcoholic hepatitis?

Answer 27

Question 28

Alcoholic Liver Disease:

What are the macroscopic and microscopic characteristics of Alcoholic Cirrhosis?

Answer 28

Question 29

Genetic Causes of Cirrhosis:

What is the incidence, age, pathophysiology and histology of Haemochromatosis?

Answer 29

Question 30

Genetic Causes of Cirrhosis:

What are the signs/symptoms and investigations of Haemochromatosis?

Answer 30

Question 31

Genetic Causes of Cirrhosis:

What is the incidence, age, pathophysiology and histology of Wilson’s Disease?

Answer 31

Question 32

Genetic Causes of Cirrhosis:

What are the signs/symptoms and investigations of Wilson’s Disease?

Answer 32

Question 33

Genetic Causes of Cirrhosis:

What is the incidence, age, pathophysiology and histology of Alpha 1 Antitrypsin Deficiency?

Answer 33

Question 34

Genetic Causes of Cirrhosis:

What are the signs/symptoms and investigations of Alpha 1 Antitrypsin Deficiency?

Answer 34