Immunology: Autoantibodies & HLA associations Flashcards

1
Q

HLA Associations:

What is the susceptibility allele and risk factor increase for:

  1. Ankylosing spondylitis
  2. Goodpasture’s syndrome
  3. Grave’s Disease
  4. Systemic Lupus Eyrthematosis (SLE)
  5. Type I Diabetes
  6. Rheumatoid Arthritis
A
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2
Q

HLA Associations:

What are PTPN22 and CTLA4 associated with?

A
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3
Q

Important other diseases:

What is/are the aetiology, symptoms, investigations and complications for Limited cutaneous scleroderma (CREST Syndrome)?

A
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4
Q

Important other diseases:

What is/are the aetiology, symptoms, investigations and complications for Diffuse cutaneous scleroderma?

A
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5
Q

Important other diseases:

What is/are the epidemiology and symptoms of Sjogren’s Syndrome?

A
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6
Q

Important other diseases:

What is/are the aetiology, symptoms, investigations and complications for IPEX syndrome?

A
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7
Q

Important other diseases:

What is/are the aetiology and symptoms of Coeliac Disease?

A
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8
Q

Important other diseases:

What are the investigations for Coeliac Disease?

A
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9
Q

Important other diseases:

What is/are the complications, epidemiology, genetics and gold standard investigation for Coeliac Disease?

A
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10
Q

List of Autoantibodies:

What are the 4 extractable extracelular nuclear antibodies?

A
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11
Q

List of Autoantibodies:

What are the antibodies for Antiphospholipid Syndrome (Hugh’s Syndrome)?

A
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12
Q

List of Autoantibodies:

What are the autoantibodies for Autoimmune hepatitis?

A
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13
Q

List of Autoantibodies:

What are the autoantibodies for Autoimmune haemolytic Anaemia?

A
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14
Q

List of Autoantibodies:

What are the autoantibodies for Autoimmune Thrombocytopenic Purpura?

A
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15
Q

List of Autoantibodies:

What are the autoantibodies for Churg-Strauss Syndrome (eGPA)?

A
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16
Q

List of Autoantibodies:

What are the autoantibodies for Coeliac disease?

17
Q

List of Autoantibodies:

What are the autoantibodies for Congenital heart block in infants of mothers with SLE?

18
Q

List of Autoantibodies:

What are the autoantibodies for Dermatitis herpetiformis?

19
Q

List of Autoantibodies:

What are the autoantibodies for Dermatomyositis?

20
Q

List of Autoantibodies:

What are the autoantibodies for Diffuse Cutaneous Scleroderma?

21
Q

List of Autoantibodies:

What are the autoantibodies for Goodpasture’s Syndrome?

22
Q

List of Autoantibodies:

What are the autoantibodies for Graves Disease?

23
Q

List of Autoantibodies:

What are the autoantibodies for Hashimoto’s Thyroiditis?

24
Q

List of Autoantibodies:

What are the autoantibodies for Limited cutaneous scleroderma (CREST)?

25
**_List of Autoantibodies:_** What are the autoantibodies for Microscopic Polyangiitis (MPA)?
26
**_List of Autoantibodies:_** What are the autoantibodies for Mixed connective tissue disease?
27
**_List of Autoantibodies:_** What are the autoantibodies for Myasthenia Gravis?
28
**_List of Autoantibodies:_** What are the autoantibodies for Pernicious anaemia?
29
**_List of Autoantibodies:_** What are the autoantibodies for Polymyositis?
30
**_List of Autoantibodies:_** What are the autoantibodies for Primary biliary cirrhosis?
31
**_List of Autoantibodies:_** What are the autoantibodies for Rheumatoid Arthritis?
32
**_List of Autoantibodies:_** What are the autoantibodies for Sjogren’s syndrome?
33
**_List of Autoantibodies:_** What are the autoantibodies for Systemic Lupus Erythematosis?
34
**_List of Autoantibodies:_** What are the autoantibodies for Type 1 Diabetes Militus?
35
**_List of Autoantibodies:_** What are the autoantibodies for Wegener’s Granulomatosis (GPA)?
36
**_Important other diseases:_** What is/are the assocaited antibodies and investigations for Sjogren's Syndrome?