Haematology: Haemolytic Anaemias

Question 1

Haemolytic Anaemias:

What is the definition of haemolytic anaemia?

Answer 1

Question 2

Haemolytic Anaemias:

What are the features of all, intravascular and extravascular haemolytic anaemias?

Answer 2

Question 3

Haemolytic Anaemias:

What are the causes of inherited and acquired anaemia?

Answer 3

Question 4

Haemolytic Anaemias:

What are the features of hereditary spherocytosis?

Answer 4

Question 5

Haemolytic Anaemias:

What are the features of Hereditary elliptocytosis?

Answer 5

Question 6

Haemolytic Anaemias:

What are the features of Southeast asian Ovalocytosis?

Answer 6

Question 7

Haemolytic Anaemias:

What is the inheritance, epidemiology of G6PD deficiency and what are the features of its attacks?

Answer 7

Question 8

Haemolytic Anaemias:

What are the investigations and management of G6PD deficiency?

Answer 8

Question 9

Haemolytic Anaemias:

What are the features of pyruvate kinase deficiency?

Answer 9

Question 10

Sickle Cell Anaemia:

Outline the genetics and main subtypes of Sickle Cell Anaemia

Answer 10

Question 11

Sickle Cell Anaemia:

What are the important features of Haemolysis and Vaso Occlusion in Sickle cell anaemia?

Answer 11

Question 12

Sickle Cell Anaemia

Outline the typical initial presentations of sickle cell anaemia

How do Sick cells change in low Oxygen?

Answer 12

Question 13

Sickle Cell Anaemia

What are the rarer subtypes of Sickle Cell Anaemia?

Answer 13

Question 14

Sickle Cell Anaemia:

What are the typical symptoms in Children, teens and Adults with Sickle cell anaemia?

Answer 14

Question 15

Sickle Cell Anaemia:

What are the investigations and management of sickle cell anaemia?

Answer 15

Question 16

Haemoglobinopathies:

What is the definition of thalassaemia?

Answer 16

Question 17

Haemoglobinopathies:

What is the diagnosis and treatment of Thalassaemia?

Answer 17

Question 18

Haemoglobinopathies:

What are the subtypes of Beta Thalassaemia?

Answer 18

Question 19

Haemoglobinopathies:

What is/are the genetics and presentation of Beta Thalassaemia?

Answer 19

Question 20

Haemoglobinopathies:

What are the features of Alpha Thalassaemia?

Answer 20

Question 21

Acquired Haemolytic Autoimmune Anaemias:

What are the types of autoimmune acquired haemolytic anaemia?

Answer 21

1. Autoimmune
   
   1. Warm Autoimmune Haemolytic Anaemia
   2. Cold Agglutinin Disease
   3. Paroxysmal cold haemoglobinuria
2. Nonimmune Paroxysmal nocturnal haemoglobinuria
   
   1. Microangiopathic Haemolytic Anaemia
   2. Thrombocytopenic Purpura
   3. Haemolytic Uraemic syndrome

Question 22

Acquired Haemolytic Autoimmune Anaemias:

What are the features of Warm and Cold autoimmune haemolytic anaemia?

Answer 22

Question 23

Acquired Haemolytic Autoimmune Anaemias:

What are the causes of Warm and Cold autoimmune haemolytic anaemia?

Answer 23

Question 24

Acquired Haemolytic Autoimmune Anaemias:

What is the management of Warm and Cold autoimmune haemolytic anaemia?

Answer 24

Question 25

Acquired Haemolytic Autoimmune Anaemias:

What are the features of Paroxysmal cold haemoglobinuria (PCH)?

Answer 25

Question 26

Acquired Non–Immune Haemolytic Anaemias:

What is/are the aetiology and symptoms of Paroxysmal nocturnal haemoglobinuria?

Answer 26

Question 27

Acquired Non–Immune Haemolytic Anaemias:

What is/are the investigations and management of Paroxysmal nocturnal haemoglobinuria?

Answer 27

Question 28

Acquired Non–Immune Haemolytic Anaemias:

What is/are the aetiology and causes of Microangiopathic Haemolytic Anaemia (MAHA)?

Answer 28

Question 29

Acquired Non–Immune Haemolytic Anaemias:

What is/are the aetiology and causes of Thrombotic thrombocytopenia purport?

Answer 29

Question 30

Acquired Non–Immune Haemolytic Anaemias:

What is/are the aetiology and causes of Haemolytic Uraemic Syndrome?

Answer 30