Hypersensitivities and Autoimmune Disorders Flashcards

1
Q

Pre-Assessment

Question 1 of 5

Which diagnostic test would be ordered by the primary healthcare provider to confirm sarcoidosis?

Electrocardiogram
Blood test
Chest x-ray
Magnetic resonance imaging

A

Chest x-ray

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2
Q

Pre-Assessment

Question 2 of 5

A client is suffering from scleroderma. Which symptom might develop in the client on exposure to cold?

Raynaud’s phenomenon
Joint swelling
Calcinosis
Kaposi’s sarcom

A

Raynaud’s phenomenon

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3
Q

Pre-Assessment

Question 3 of 5

A registered nurse is teaching a student nurse about rheumatoid arthritis. Assess the statements made by the student nurse and choose the statement that indicates the need for further teaching.

“Characteristic deformities occur in the joints of the hands.”
“Swan neck and Boutonniere deformity of fingers are observed.”
“Rheumatoid arthritis and osteoarthritis have similar etiologies.”
“Joint pain is worse in the morning or upon waking.”

A

“Rheumatoid arthritis and osteoarthritis have similar etiologies.”

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4
Q

Pre-Assessment

Question 4 of 5

A client with rheumatoid arthritis has Sjögren’s syndrome. What should be included in the care plan of the client to treat Sjögren’s syndrome? Select all that apply.

Administration of ophthalmic solution
Thymus gland transplant
ART regimen
Including citrus fruits in the diet
Administration of medications to stimulate salivary gland function
A

Administration of ophthalmic solution

Administration of medications to stimulate salivary gland function

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5
Q

Pre-Assessment

Question 5 of 5

A client develops itching, skin erythema, and tongue edema immediately after having peanuts. On examination, the client is found to have low blood pressure. What medication would be given to treat this condition? Select all that apply.

Intranasal corticoid
Glucocorticoid
Antihistamine
Epinephrine
Aspirin
A

Glucocorticoid
Antihistamine
Epinephri

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6
Q

Question 1 of 8

You are a clinician working at a local family practice clinic. Karen, a 34-year-old woman, has visited the clinic 3 times in the past 3 months with a variety of complaints. After researching her symptoms online, Karen has come to the conclusion that she is suffering from an autoimmune disease.

As you take Karen’s recent health history, she makes several comments about what she has read online. Which of the following statements from Karen about autoimmune diseases is true?
“Certain autoimmune diseases, like rheumatoid arthritis, are more common in women.”
“Autoimmune diseases are genetic. They just appear out of nowhere and for no apparent reason.”
“Autoimmune diseases affect only one organ in the body at a time, and it is usually the lungs.”
“There are no diagnostic tests available for autoimmune diseases.”

A

Certain autoimmune diseases, like rheumatoid arthritis, are more common in women.”

Some autoimmune diseases, such as rheumatoid arthritis, are more common in women. A genetic predisposition does exist for some autoimmune diseases. Autoimmune diseases may be systemic or organ specific, and some have very specific diagnostic tests and criteria.

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7
Q

Question 2 of 8

With all her research, Karen thinks she may have systemic lupus erythematosus (SLE). You listen to Karen describe her signs and symptoms. Which of the following would be supportive of Karen’s potential self-diagnosis? Select all that apply.

In cold weather, Karen reports if she does not have gloves on, her fingers turn white and cold.
Her eyes and mouths are “constantly” dry.
She develops hives when outside in the summer.
She has severe joint pain and swelling.
She is “extremely” tired and lost 8 pounds since she began seeking medical care 3 months ago.

A

In cold weather, Karen reports if she does not have gloves on, her fingers turn white and cold.

She has severe joint pain and swelling.

She is “extremely” tired and lost 8 pounds since she began seeking medical care 3 months ago.

Raynaud’s phenomenon, cold and white fingers, may accompany SLE. Joint pain and swelling, severe weight loss, and fatigue are common signs and symptoms of SLE. Hives are a type I hypersensitivity.

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8
Q

Question 3 of 8

Which of the following signs would you find during Karen’s examination to support the diagnosis of SLE?
Tightening of the skin in the facial area
Swab neck deformity of the hands
Butterfly-shaped rash on cheeks
Dry eyes

A

Butterfly-shaped rash on cheeks

A butterfly-shaped rash across the cheeks commonly appears in those affected by SLE. Swan neck deformities are common in rheumatoid arthritis. Tightening of the skin in the facial area may occur with scleroderma, and dry eyes are a sign of Sjogren’s syndrome.

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9
Q

Question 4 of 8

Karen continues providing her health history, including that she is severely allergic to pollen. Which type of hypersensitivity does this represent?
Type I
Type II
Type III
Type IV
A

Type I

Type I hypersensitivities are commonly known as “allergens.”

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10
Q

Question 5 of 8

Karen also tells you that she just recently developed a “horrible, disgusting” rash, which may be from accidentally touching some poison ivy while weeding her garden. Karen states she thought she was fine because she didn’t see a rash, but 2 days later she began to itch and found a rash had formed. What type of hypersensitivity does Karen’s rash represent?
Type I
Type II
Type III
Type IV
A

Type IV
Type IV hypersensitivities, which are T-cell mediated, are considered “delayed hypersensitivities” because they develop days after exposure.

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11
Q

Question 6 of 8

You find Karen’s descriptions helpful but want to obtain some more definitive information about her health. What laboratory tests would you order to help with the diagnosis of SLE? Select all that apply.
RF positive
ANA elevation
CRP elevation
ESR
Anti-dsDNA
A

ANA elevation
CRP elevation
ESR
Anti-dsDNA

RF stands for rheumatoid factor and does not help with SLE diagnosis. Although there is no single diagnostic test for SLE, elevated antinuclear antibody (ANA), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and anti-dsDNA all point to SLE.

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12
Q

Question 7 of 8

During the consultation, Karen continually rubs her eyes. She says that her eyes are constantly dry and irritated, and that she has problems swallowing. She asks you if these are signs of SLE. Which of the following conditions do you tell her is associated with dry eyes and mouth?
Scleroderma
Sjogren’s syndrome
Polyarteritis nodosa
Sarcoidosis
A

Sjögren’s syndrome

Sjorgen’s syndrome attacks the lacrimal and salivary glands leading to dry eyes and dry mouth

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13
Q

Question 1 of 5

Which immunoglobulin is primarily responsible for an allergic response?

IgE
IgG
IgD
IgM

A

IgE

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14
Q

Question 2 of 5

Which of the following may be a sign of systemic lupus erythematosus (SLE)?

Splayed hand appearance
Watery eyes and rhinorrhea
Dry eyes
Butterfly-shaped rash across cheeks

A

Butterfly-shaped rash across cheeks

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15
Q

Question 3 of 5

Which type of hypersensitivity presents as a “delayed” reaction, such as with poison ivy?

Type II hypersensitivity
Type IV hypersensitivity
Type III hypersensitivity
Type I hypersensitivity

A

Type IV hypersensitivity

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16
Q

Question 4 of 5

Which of the following statements is incorrect?

Rheumatoid arthritis may affect tissues other than the joints of the hand.
Men are more commonly affected by autoimmune diseases than women.
Some autoimmune disorders are systemic.
Genetic predisposition plays a role in the development of autoimmune diseases.

A

Men are more commonly affected by autoimmune diseases than women

17
Q

Question 5 of 5

Which condition features the accumulation of fibrous tissue in the skin?

Scleroderma
Systemic lupus erythematosus
Type I hypersensitivity
Raynaud’s phenomenon

A

Scleroderma

18
Q

Immunodeficiency Question 1 of 5

A registered nurse is teaching a student nurse about the causes of IgA deficiency. Which statement by the student indicates the need for further teaching?

“IgA deficiency does not mean inadequate IgM and IgG levels are present.”
“Some infections increase susceptibility of IgA deficiency.”
“IgA deficiency is a very rare primary immune disorder.”
“IgA deficiency can be caused by exposure to benzene.

A

IgA deficiency is a very rare primary immune disorder.”

19
Q

Immunodeficiency Question 2 of 5

Hypogammaglobulinemia is ___________________. Select all that apply.

a disorder of B cells only.
a disorder of both B and T cells.
always a primary immunodeficiency.
a condition that can be acquired or caused by genetic defects.
a disorder of T cells only.
A

A disorder of B cells only.

a condition that results in low Ig levels following vaccination

20
Q

Immunodeficiency Question 3 of 5

What may you expect in DiGeorge syndrome? Select all that apply.

Life-threatening condition
Poorly developed thymus gland
Mild signs and symptoms
Elevated T cell levels
Genetic cause
A

Life-threatening condition
Poorly developed thymus gland
Genetic cause

21
Q

Immunodeficiency

In HIV, the most accurate measurement of the degree of immune system impairment is _________________.

Western blot
CD4 count
Southern blot
HIV antibody titer

A

CD4 count

22
Q

Immunodeficiency Question 5 of 5

Which of the following results in classification of AIDS?

Seroconversion for HIV antibody.
CD4 count of 190 cells per microliter and Pneumocystic infection.
Significant increase in the CD4:CD8 ratio.
CD4 levels greater than 500 cells per microliter.

A

CD4 count of 190 cells per microliter and Pneumocystic infection.

23
Q

Question 8 of 8

If Karen is diagnosed with SLE, which of the following are possible treatment options? Select all that apply.
NSAIDs
Methotrexate
DMARDs
Ophthalmic solutions
Immunosuppressants
A

NSAIDs
Methotrexate
Immunosuppressants

NSAIDs, methotrexate, and immunosuppressants are all common treatment options for SLE. Disease-modifying antirheumatic drugs (DMARDs) are used to treat rheumatoid arthritis. If Karen does have Sjogren’s syndrome, ophthalmic solutions may help, but these are not standard treatments for SLE.