Hormones and Pancreatitis that act in digestion Flashcards
Cholecystokinin is produced?
Duodenal Mucosa
What is Cholecystokinin’s role in the Stomach?
Inhibits Stomach Secretory Activity
What is Cholecystokinin’s role in the Liver?
Stimulating the production of bile in the liver as well as its release from the gall bladder.
What is Cholecystokinin’s role in the Pancreas?
Stimulates pancreatic enzyme secretion
What is Cholecystokinin’s role in the hepatopancreatic sphincter/ sphincter of Oddi?
Relaxes Sphrincter to allow bile and pancreastic juices to enter duodneum
What is Cholecystokinin’s role in the Gallbladder?
Stimulates the organ to contract and release Bile (Stored)
Glucose-dependent insulinotropic polypeptide is produced where?
Duodenal Mucosa
What is Glucose-dependent insulinotropic polypeptide’s role in the stomach?
Inhibits HCL production
What is Glucose-dependent insulinotropic polypeptide’s role in the pancreas?/ What cells does it target?
Beta Cells; stimulates Insulin release
Where is Gastrin produced?
Stomach Mucosa
What is Gastrin’s role in the stomach? What cells does it target?
Parietal Cells, Increases HCL Secretion (Stimulates Gastric emptying)
What is Gastrin’s role in the Sm. intestines?
Stimulates contraction of intestinal muscle
What is Gastrin’s role in the Lg. intestines?
Stimulates Mass Movements
What valve does Gastrin have a Relaxation impact on?
Ilieocecal Valve
What is Histamine’s Role in the stomach?
Activates Parietal Cells to release HCL
What is intestinal Gastrin’s role in the stomach?
Stimulates Gastric glands and motility
Where does Motilin act upon? Whats its function?
Proximal Duodenum- Stimulates Migrating motor Complex
What stimulates the production for CCK?
Fatty Chyme
What stimulates the production for GIP?
Fatty Chyme
What stimulates the production for Gastrin?
ACH Released by nerve fibres
What stimulates the production for Histamine?
Food in stomach
What stimulates the production for Intestinal Gastrin?
Acid and partily digested food in Duodenum
What stimulates the production for Motilin?
Fasting
What stimulates the production for secretin?
Acid Chyme
What stimulates the production for Serotonin?
Food in the stomach
What stimulates the production for Somatostatin?
Food in stomach; Stimulated by sympathetic nerve fibres
What stimulates the production for Vasoactive intestinal peptide (VIP)?
Chyme Containing partilly digestive foods
What is the site of production for Vasoactive intestinal peptide (VIP)?
Enteric Neurons
What does Vasoactive intestinal peptide (VIP) do in the Sm. Intestines?
Stimulates Buffer Secretion
Increases blood flow through intestinal capillaries
Relaxes intersticial smooth muscle
What does Vasoactive intestinal peptide (VIP) do in the stomach?
inhibits Secretion
What does Vasoactive intestinal peptide (VIP) do in the pancreas?
Increases Secretion
Where is Somatostatin produced?
Stomach Mucosa, Dudoneal Mucosa
What is Somatostatin’s role in the stomach?
Inhibits gastric Secretion of all products
What is Somatostatin’s role in the Pancreas?
Inhibits Secretion
What is Somatostatin’s role in the Sm. Intestines?
Inhibits GI Blood flow; thus inhibits intestinal absorbption
What is Somatostatin’s role in the Gallbladder/ Liver?
Inhibits Bile release and contraction
What is Serotonin’s role in the Stomach?
Causes contraction of stomach muscles
What is Secretin’s role in the Stomach?
inhibits gastric glands secretion and gastric Motility
What is Secretin’s role in the Pancreas?
Increase output of pancreati juices that are rich in?
Bicarbonate ions, and Potentiates CCk action
What is Secretin’s role in the Liver?
Increase Bile output
What is the tole of Motilin in the proximal Duodenum?
Stimulates Migrating motor Complex
