Histology of Cartilage and Bone Flashcards

1
Q

Four properties of cartilage are?

A

Modified connective tissue
Avascular (nutrients diffuse through matrix)
Resists compression
Perichondrium is rich in blood vessels

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2
Q

Four properties of perichondrium are?

A

Composed of cells & matrix
Absent in fibrocartilage
Ensheaths the cartilage
Houses the blood vessels that nourish chondrocytes

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3
Q

Three functions of chondroblasts are?

A

Chondrocytes progenitor
Lines border between perichondrium and matrix
Produce the intercellular matrix & collagen fibers

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4
Q

Four properties of chondrocytes are?

A

Mature cartilage cell
Reside in space called the lacuna
Basophilic
Isogenous cell group

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5
Q

Two functions of chondrocytes are?

A

Synthetically active, secrete matrix

Synthesize type II collagen, proteoglycans & chondronectin

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6
Q

Territorial matrix surrounds the?

A

Lacuna

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7
Q

Cartilage Matrix is divided into?

A

Fibers

Ground substance

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8
Q

Cartilage fibers are?

A

Collagenous and elastic

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9
Q

Cartilage ground substance is made up of?

A

Glycosaminoglycans (chondroitin sulfates etc)
Proteoglycans
Water

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10
Q

Cartilage matrix provides?

A

Rigidity
Elasticity
Resilience

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11
Q

Cartilage matrix is?

A

Basophilic

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12
Q

Cartilage matrix shows?

A
Territorial matrix(surrounds lacuna)
Interterritorial matrix
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13
Q

Cartilage growth is divided into?

A

Interstitial

Appositional

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14
Q

Interstitial cartilage growth is newly formed cartilage growing by?

A

Multiplication of cells throughout its substance

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15
Q

Addition of new cartilage over the surface of existing cartilage is?

A

Appositional cartilage growth

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16
Q

The types of cartilage are?

A

Hyaline
Elastic
Fibrous

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17
Q

Hyaline cartilage is found in?

A

Tracheal rings
Larynx
Nasal septum etc

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18
Q

Hyaline cartilage matrix is composed of?

A

Collagen type II

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19
Q

Hyaline cartilage cells are present singly or in groups of?

A

2 or 4 cells inside lacunae

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20
Q

Hyaline cartilage ground substance is?

A

Homogeneous

Basophilic

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21
Q

The function of hyaline cartilage is?

A

Supportive

22
Q

Elastic cartilage is found in?

A

Auricle
epiglottis
Auditory tube

23
Q

Elastic cartilage cells are ?

A

Larger
More numerous
Packed more closely

24
Q

Elastic cartilage matrix is composed of?

A

Elastic fibers

Collagen type II

25
Elastic cartilage ground substance is rich in?
Elastic fibers
26
The function of Elastic cartilage is?
Supportive with resilience
27
Elastic fibers stain with?
Orcein
28
Fibrocartilage is found in?
Intervertebral discs Pubic symphysis Articular disc of TM(temporomandibular) joint
29
Fibrocartilage cells are?
Fewer Smaller Scattered singly not in rows
30
Fibrocartilage matrix contains?
Collagen type I & II
31
Fibrocartilage ground substance is?
Acidophilic
32
The function of fibrocartilage is?
Supportive with tensile strength
33
Two clinical correlates are?
Osteoarthritis | Pseudoachondroplasia
34
Four properties of bones are?
Modified connective tissue Provide support & protection to vital organs Forms skeletal framework Highly vascularized & mineralized
35
Bone is composed of?
Cells Fibers Ground substance
36
Bone cells are?
Osteogenic cells Osteoblasts Osteocytes Osteoclasts
37
Bone fibers contain?
Collagen type I
38
Bone ground substance contains
Proteoglycans | Glycoproteins
39
Bone matrix is a mixture of___&____?
Organic(collagen) | Inorganic (calcium phosphate)
40
90% of bone is?
Matrix
41
10% of bone is
Osteocytes
42
Rings around the central canal that also serve as sites of lacunae are called?
Lamellae
43
Cavities containing osteocytes arranged in concentric rings is called?
Lacunae
44
Tiny canals that radiate from the central canal to lacunae and form a transport system are called?
Canaliculi
45
The morphofunctional unit of the bone is called?
Osteon or Haversian system
46
The lamellar pattern of compact bone in order is?
Haversian system Interstitial lamellae Circumferential lamellae
47
Clinical correlates are?
``` Scurvy Tickets Osteomalacia Osteoporosis Osteogenesis imperfecta ```
48
What vitamin and mineral are essential for formation and maintenance of bones?
Vitamin D | Calcium
49
The blood vessels and nerves go inside the bone through the?
Haversian canal or central canal
50
Any of the small channels in the bone that transmit blood vessels from the periosteum into the bone and communicates with the haversian canals is called?
Volkmann's canals