Blood Formed Elements Flashcards
______ is a unique form of connective tissue
Blood
The three types of Blood formed elements are?
Red blood cells (larger %)
Platelets
White blood cells(smaller %)
All three blood formed elements are suspended in a liquid medium called______?
Plasma
The main function of blood is?
Transport
A proteinaceous solution which contains three main types of protein: albumin, globulin & fibrinogen is called?
Plasma
____ makes up about 55% of the blood volume
Plasma
When clotted & defibrinated, plasma becomes?
Serum
Red blood cells(erythrocytes) are about _____ in man and _____ in woman?
5.2 - 5.8 million mm cube, 4.3-5.2 million mm cube
RBC have a______disc shape with a diameter of ____ and a thickness of _____
Biconcave
7.5 micrometer
2 micrometer
RBC are devoid of _____&_____
Nucleus
Cytoplasmic organelles
RBC form stacks called?
Rouleaux
RBC have a smooth, rounded ______ with a central ______
Contour
Depression
Life span of RBC is?
100-120 days
RBC cytoskeleton is made up of the protein, ______ which maintains the shape
Spectrin
RBC are removed from circulation, mainly by macrophages of the______, ______, and _______
Spleen
Liver
Bone marrow
RBC is the determinant of?
Blood group
Platelets (thrombocytes) are about________ in the body
200,000-400,000 mm cube
Platelets are small and ________
Non-nucleated
Platelets are rounded or ovoid in shape with a diameter of ______
2-5 micrometer
Platelets life span is?
10 days
White blood cells( leukocytes) contain?
Nuclei & cytoplasmic organelles (true cells)
WBC are about ______ in a healthy adult
5000-9000 mm cube
Classification of WBC according to granularity is divided into?
Granulocytes
Agranulocytes
Granulocytes are divided into?
Neutrophils, Eosinophils, Basophils
Agranulocytes are divided into?
Monocytes
Lymphocytes
Classification of WBC according to shape of nucleus is divided into?
Polymorphonuclear: more than one nucleus eg granulocytes
Mononuclear: single non-lobed nucleus eg agranulocytes
Neutrophils have a differential count of?
50-70
Neutrophils have a life span of?
1-4 days
Neutrophils nucleus has ____ lobes
3-5
Neutrophils function is to?
Kill and phagocytose Bacteria
Neutrophils specific granules are?
Light/faint pink
Eosinophils have a _____ nucleus
Bilobed
Eosinophils specific granules are?
Red/dark pink
Eosinophils differential count is?
1-4
Eosinophils life span is?
1-2 weeks
Eosinophils function is to?
Kill parasites and modulate local inflammation
Basophils have a ______ or _______ nucleus
Bliobed or S-shaped
Basophils specific granules are?
Dark blue /purple
Basophils differential count is?
0.5-1
Basophils life span is?
Several months
Basophils function is to?
Modulate inflammation & release histamine during allergy
Lymphocytes have a _____ nucleus
Spherical
Lymphocytes and Monocytes have no ________
Specific granules
Lymphocytes differential count is
20-40
Lymphocytes life span is?
Hours to many years
Lymphocytes function is to?
Act as effector and regulatory cells for adaptive immunity
Monocytes have an ________ or ________ nucleus
Indented or C- shaped
Monocytes have a differential count of?
2-8
Monocytes life span is?
Hours to years
Monocytes major function is to?
Act as precursor of macrophages and other mononuclear phagocytic cells
Neutrophils have_____ granules
Three
The primary (first formed) granules of neutrophils contain?
Acid hydrolases & myeloperoxidase that is antibacterial
The secondary granules of neutrophils contain?
Substances that are secreted into extracellular spaces and stimulate an inflammatory reaction
Tertiary neutrophils granules are concerned with
The adhesion of leukocytes & their phagocytosis