Blood Group System

Question 1

____ discovered the ABO blood group system in 1901

Answer 1

Landsteiners

Question 2

In Landsteiners law, if an ____ is present on a patient’s red blood cells, the corresponding _____ will not be present in the patient’s plasma, under normal conditions

Answer 2

antigen(Ag)

Antibody (Ab)

Question 3

At least ___ commonly occuring antigens have been found on the cell membrane of RBC’s

Answer 3

300

Question 4

The basis of blood grouping depends on?

Answer 4

Multiplicity of Antigens in the blood cells

Question 5

The two groups or systems of antigens that cause transfusion reactions more than others are?

Answer 5

ABO system

Rh system

Question 6

Naturally occurring antibodies are what class?

Answer 6

IgM class

Question 7

IgM antibodies class, are antibodies capable of?

Answer 7

Agglutination

Question 8

Almost all normal healthy individuals above 3-6 months of age have naturally occurring antibodies to?

Answer 8

The ABO antigens that they lack

Question 9

An individual inherits ___ ABO gene from ___ parent which determine their antigens

Answer 9

One

Each

Question 10

A heterozygous individual will have what types of genes?

Answer 10

AO

BO

Question 11

A homozygous individual will have what types of genes?

Answer 11

AA

BB

Question 12

Phenotype is the actual expression of the?

Answer 12

Genotype

Question 13

Genotype is the actual ___ which can only be determined by family studies

Answer 13

Inherited genes

Question 14

The possible offspring of two homozygous A parents are?

Answer 14

AA

Question 15

The possible offspring of two heterozygous A parents are?

Answer 15

AA
AO
OO

Question 16

The possible offspring of one heterozygous A parent and one homozygous A parent are?

Answer 16

AA

AO

Question 17

The possible offspring of one heterozygous B parent and one homozygous B parent are?

Answer 17

BB

BO

Question 18

The possible offspring of two heterozygous B parents are?

Answer 18

BB
BO
OO

Question 19

The possible offspring of two homozygous B parents are?

Answer 19

BB

Question 20

The relative frequency of O blood group is?

Answer 20

47%

Question 21

The relative frequency of A blood group is?

Answer 21

41%

Question 22

The relative frequency of B blood group is?

Answer 22

9%

Question 23

The relative frequency of AB blood group is?

Answer 23

3%

Question 24

Group O has ___ antibodies with ___ antigens present

Answer 24

A and B

O

Question 25

Group A has ___ antibodies with no ___ antigens present

Answer 25

B

Question 26

Group B has ___ antibodies with no ___ antigens present

Answer 26

A

Question 27

Group AB has ___ antibodies with ___ antigens present

Answer 27

No ABO | A and B

Question 28

Group O is also known as?

Answer 28

Universal donnor

Question 29

Group AB is also known as the?

Answer 29

Universal recipient

Question 30

There are more than ___ different Rh antigens

Answer 30

50

Question 31

Rh system was identified by ___ in 1940

Answer 31

Landsteiner and Weiner

Question 32

The presence and absence of Rh antigen D on RBCs is referred to as?

Answer 32

D positive and D negative respectively

Question 33

Four additional Rh antigens are?

Answer 33

C c E e

Question 34

Some blood transfusion reactions are?

Answer 34

``` Acute Delayed Iron overload Alloimmunization Non-immune haemolysis Hypotensive reactions Acute pain reaction ```

Question 35

Acute Blood transfusion reactions are caused by?

Answer 35

ABO incompatibility

Question 36

An Acute Blood transfusion reaction symptom is?

Answer 36

Intravascular haemolysis

Question 37

Delayed blood transfusion reaction is mostly caused by?

Answer 37

Rh problems

Question 38

A Delayed blood transfusion reaction symptom is

Answer 38

Extravascular haemolysis but may be intravascular