HIIT Exercise- ROS, Lactate and H+ Transport W2

Question 1

What facilitates transport of Lactate and H+?

Answer 1

MCT proteins
(MCT4 and MCT1)

Question 2

Where is MCT4 proteins most prevalent in and what do they do?

Answer 2

Type II fibres
Responsible for lactate transport out of glycolytic system

Question 3

Where is MCT1 proteins most prevalent in and what do they do?

Answer 3

Type I fibres
Lactate uptake into oxidative cells

Question 4

What training increases MCT1 proteins?

Answer 4

HIIT
Endurance training steady state

Question 5

What training increases MCT4 proteins?

Answer 5

HIIT

Question 6

What is ROS?

Answer 6

Reactive Oxygen Species

Alters ryanodine receptor
Reduces SERCA activity
Modifies the structure and function of myofilaments

Question 7

What does ROS reducing SERCA activity influence?

Answer 7

Reduces the re-uptake of Ca2+ into the SR

Question 8

What is NAC?

Answer 8

Supports the resynthesis of the non-enzymatic antioxidant glutathione

Question 9

How does ROS modify the structure/function of myofilaments?

Answer 9

Reduces force production