HIIT Exercise- Acidosis, Extracellular Potassium W2

Question 1

What happens when K+ is released and accumulated in the extracellular space?

Answer 1

Leads to depolarization of membrane potential
Causes membrane excitability
Reduces force

Question 2

What counteracts the loss excitability in order to maintain high rates of power output?

Answer 2

Rapid restoration of Na+ and K+

Question 3

What enhances K+?

Answer 3

Metabolic acidosis

Question 4

How can extracellular potassium cause fatigue?

Answer 4

Imbalance in muscle K+ homeostasis
Impaired excitation of sarcolemma

Question 5

What negative effects can Metabolic Acidosis have?

Answer 5

Impair muscle contraction
Reduce enzyme activity

Question 6

How does metabolic acidosis impair muscle contraction?

Answer 6

Reduces Ca2+ releasement
Reduces Voltage sensor activation
Reduces Ca2+ binding to Troponin C

Question 7

How is metabolic acidosis caused?

Answer 7

When H+ ions dissociate from lactate

Question 8

What is acidosis?

Answer 8

Increase in lactate and H+

Question 9

What happens to acidosis during HIT?

Answer 9

Dissociates into lactate anions and H+