Hepatocilliary System I (liver) Flashcards
radilogical modalities for hepatobiliary system:
- US, CT, MRI, SPECT
- MRCP (non invasive)
- ERCP (invasive)
- Percutaneous transhepatic cholangiogram
MRCP = MR cholangiopancreatography
ERCP = Endoscopic retrograde cholangiopancreatogram
examples for Diffuse liver diseases
- hepatic steatosis
- hepatic fibrosis
- infections
Uss of hepatic steatosis:
++ parenchymal echogenicity
Loss of visualization of the portal triads
Severe steatosis causes sound-beam attenuation, which will obscure visualization of the deep portions of the liver, & lesions like metastasis.
Hepatic steatosis on CT
decreased attention of hepatic parenchyma
HU is lower than the speen by more than 10 on non-contrast exams (and >25 HU with contrast)
Appearanceof Hyperdense vessels on non contrast exam
My obscure lesions that are normally hypodense compared to background liver
Moderate to severe steatosis if either (HU):
For non-contrast CT:
Liver attenuation < 40 HU
Liver attenuation > 10HU less than spleen
With IV contrast (portal venous phase):
Liver attenuation > 25 HU less than spleen
Steatosis on MRI
Loss of signal on out-of-phase imaging relative to in-phase imaging
describe hepatic steatosis radiologically (review)
- by US –> increased parenchymal echogenicity
- by CT –> Decreased attenuation (less than 40 HU)
- by MRI –> loss of signal on out-of-phase imaging relative to in-phase imaging.
review
HU of fatty liver compared to spleen ([HU of spleen] - [HU of fatty liver]) = …..
25 HU or more
Other MR techniques for hepatic steatosis
MR spectroscopy
MR Elastography
T1 mapping
the fatty liver may make the diagnosis of some diseases difficult radiologically, explain why?
- by US –> severe steatosis can cause sound-beam attenuation, which will obscure visualization of lesions like metastasis.
- by CT –> May obscure lesions that are normally hypodense
Role of imaging in cases of viral hepatitis
Image try to exclude biliary obstruction or neoplasm
Image evaluate parenchymal damage non-invasively
Image of …… usually sufficient to suggest dx of acute viral hepatitis and imaging surveillance of patients with hepatitis C prior to the development of heterogeneous nodular fibrotic, cirrhosis.
Ultrasound
Ultrasound has poor sensitivity and specificity for detection of:
Hepatocellular carcinoma in cirrhotic liver
Image …. or …. is mandatory for HCC surveillance among cirrhotic patients
Multiphasic Contrast-enhanced CT
MRI
Grayscale ultrasound of acute viral hepatitis
• ++ liver and spleen size
• decrease echogenicity of liver
• increase echogenicity of portal venous walls (starry sky)
• Thickened gallbladder wall
• periportal hypo-/anechoic area (hydropic swelling of hepatocytes)