Heparin (Unfractionated Heparin) ACS Medication

Question 1

Classification:

Answer 1

• Anticoagulant

Question 2

Action:

Answer 2

• Acts on antithrombin III to reduce the ability of the blood to form clots, thus preventing clot deposition in coronary arteries

Question 3

Indications:

Answer 3

• ACS
• Acute pulmonary embolism
• DVT

Question 4

Adverse Effects:

Answer 4

• Bleeding
• Thrombocytopenia
• Allergic reactions

Question 5

Contraindications:

Answer 5

• Predisposition to bleeding
• Aortic aneurysm
• Peptic ulceration
• Known sensitivity or Hx of heparin-induced thrombocytopenia, severe thrombocytopenia, sulfite sensitivity

Question 6

Dosage (Adult)
Cardiac Indications:

Answer 6

• 60 units/kg IV (Max 4000 units), followed by 12 units/kg/hr (Max 1000 units)

Question 7

Dosage (Pediatric)
Cardiac Indications:

Answer 7

• 75 units/kg followed by 20 units/kg/hr

Question 8

Dosage (Adult)
Pulmonary Embolism and DVT:

Answer 8

• 80 units/kg IV followed by 18 units/kg/hr

Question 9

Dosage (Pediatric)
Pulmonary Embolism and DVT:

Answer 9

• 75 units/kg IV followed by 20 units/kg/hr

Question 10

Special Considerations:

Answer 10

• Half life approximately 90 mins