Albuterol/Ipratropium (Combivent; Duoneb) Respiratory Medication

Question 1

Classification:

Answer 1

• Combination bronchodilator

Question 2

Action:

Answer 2

• Binds and stimulates beta2 receptors, resulting in relaxation of bronchial smooth muscle, and antagonizes the acetylcholine receptor, producing bronchodilation

Question 3

Indications:

Answer 3

• Second line treatment (if bronchodilator is ineffective) in COPD or severe acute asthma exacerbations during medical transports

Question 4

Adverse Effects:

Answer 4

• Headache
• Cough
• Nausea
• Arrhythmias
• Paradoxical acute bronchospasm

Question 5

Contraindications:

Answer 5

• Allergy to soybeans/ peanuts
• Known sensitivity to atropine, albuterol, or their respective derivatives
• Used w/ caution in Pts w/ asthma, HTN, angina, cardiac arrhythmias, tachycardia, cardiovascular disease, congenital long QT syndrome, closed angle glaucoma

Question 6

Dosage (Adults:)

Answer 6

• MDI: 8 inhalations every 20 mins for up to 3 hours
• Nebulization: 3 mL every 20 minutes for 3 doses, then as needed