Albumin

Question 1

Classification:

Answer 1

• Volume expander
• Colloid

Question 2

Action:

Answer 2

• Increases oncotic pressure in intravascular space

Question 3

Indication:

Answer 3

• Expand intravascular volume

Question 4

Adverse Effects:

Answer 4

• Allergic reaction in some Pts
• Excessive volume of fluid can result in and pulmonary edema in susceptible Pts

Question 5

Contraindications:

Answer 5

• Severe anemia/ cardiac failure in presence of normal or increased intravascular volume
• Solution appears turbid/ after 4 hours since opening the container
• Known sensitivity

Question 6

Dosage (Adult):

Answer 6

• 5% Albumin: 500-1000 mL IV, IO
  -25% Albumin: 50-200 mL IV, IO

Question 7

Dosage (Pediatric):

Answer 7

• 5% Albumin: 0.5-1 g/kg IV; Initial dose may be repeated 15-30 mins if clinical response is inadequate
• 25% Albumin: 1 g/kg IV, IO

Question 8

Special Considerations:

Answer 8

• Pts w/ history of CHF, cardiac disease, HTN, pulmonary edema should be given 5% albumin, or 25% albumin should be diluted