Digoxin (Lanoxin) Flashcards

1
Q

Classification:

A
  • Cardiac glycoside
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2
Q

Action:

A
  • Inhibits sodium-potassium-adenosine triphosphatase membrane pump, resulting in increase in calcium inside the heart muscle cell, which causes an increase in the force of the heart’s contraction
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3
Q

Indications:

A
  • CHF
  • To control the ventricular rate in chronic AF and atrial flutter
  • Narrow complex paroxysmal SVT
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4
Q

Adverse Effects:

A
  • Headache
  • Weakness
  • GI disturbances
  • Arrhythmias
  • Nausea/vomiting
  • Diarrhea
  • Vision disturbance
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5
Q

Contraindications:

A
  • Digitalis allergy
  • VT and VF
  • Heart block
  • Sick sinus syndrome
  • Tachycardia w/out heart failure
  • Pulse lower than 50-60 beats/min
  • MI
  • Ischemic heart disease
  • Pts w/ preexcitation AF or atrial flutter
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6
Q

Dosage:

A
  • Dosage is individualized
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7
Q

Special Considerations:

A
  • Low levels of serum potassium can lead to digoxin toxicity and bradycardia
  • Conditions such as administration of steroids or diuretics or vomiting and diarrhea can produce low levels of potassium and subsequent digoxin toxicity
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