Etomidate (Amidate) Analgesia/Sedation Flashcards

1
Q

Classification:

A
  • Hypnotic
  • Anesthesia induction agent
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2
Q

Action:

A
  • Exact mechanism is unknown, etomidate appears to have GABA like effects
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3
Q

Indications:

A
  • Induction for RSI and pharmacologic assisted intubation
  • Induction of anesthesia
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4
Q

Adverse Effects:

A
  • Hypotension
  • Respiratory depression
  • Pain at the site of injection
  • Temporary involuntary muscle movements
  • Frequent nausea/vomiting on emergence
  • Adrenal insufficiency
  • Hyperventilation
  • Hypoventilation
  • Apnea of short duration
  • Hiccups
  • Laryngospasm
  • Snoring
  • Tachypnea
  • HTN
  • Cardiac arrhythmias
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5
Q

Contraindications:

A
  • Known sensitivity
  • Use in pregnancy only if potential benefits justify potential risk of the fetus
  • Do not use during labor and avoid in nursing mothers
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6
Q

Dosage (Adult):

A
  • 0.2 to 0.6 mg/kg slow IV, IO (Over 30-60 seconds); 0.3 mg/kg is used in many protocols/references
  • Typical adult intubating dose of etomidate is 20 mg slow IV
  • Consider less in older adults or Pts w/ cardiac conditions
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7
Q

Dosage (Pediatric)
Older than 10 years:

A
  • Same as adult dosing
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8
Q

Dosage (Pediatric)
Younger than 10 years:

A
  • Safety has not been established
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9
Q

Special Considerations:

A
  • Etomidate is used to prepare a Pt for orotracheal intubation. Both personnel and equipment must be present to manage Pt’s airway before administration
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