Bivalirudin (Angiomax)

Question 1

Classification:

Answer 1

• Anticoagulant
• Direct thrombin inhibitor

Question 2

Action:

Answer 2

• Binds w/ thrombin to inhibit various clotting pathways

Question 3

Indications:

Answer 3

• ACS
• Cardiac surgery

Question 4

Adverse Effects:

Answer 4

• Bleeding
• Hypotension
• HTN
• Allergic reactions

Question 5

Contraindications:

Answer 5

• Predisposition to bleeding, aortic aneurysm, peptic ulceration
• Intracranial hemorrhage

Question 6

Cardiac Indications Dosage (Adult):

Answer 6

• 0.75 mg/kg bolus followed by IV infusion of 1.75 mg/kg/hour

Question 7

Special Considerations:

Answer 7

• Rapid onset
• Anticoagulant effects subside approximately 1 hour after discontinuing