Enoxaparin (Lovenox) ACS Medication

Question 1

Classification:

Answer 1

• Anticoagulant

Question 2

Action:

Answer 2

• Acts on antithrombin III to reduce ability of the blood to form clots, preventing clot disposition in coronary arteries
• Inhibits factor Xa

Question 3

Indications:

Answer 3

• ACS
• Acute pulmonary embolism
• DVT

Question 4

Adverse Effects:

Answer 4

• Bleeding
• Thrombocytopenia
• Allergic reactions

Question 5

Contraindications:

Answer 5

• Predisposition to bleeding
• Aortic aneurysm
• Peptic ulceration
• Known sensitivity
• Hx of heparin-induced thrombocytopenia, severe thrombocytopenia, sulfite sensitivity

Question 6

Dosage (Adult)
Cardiac Indications:

Answer 6

• Initial dose: 30 mg IV
• Then 1 mg/kg every two hours subcutaneously

Question 7

Dosage (Pediatric)
Cardiac Indications:

Answer 7

• 0.5 to 1.5 mg subcutaneously every 12 hours

Question 8

Dosage (Adult)
DVT:

Answer 8

• 1 mg/kg every 12 hours

Question 9

Dosage (Pediatric)
DVT:

Answer 9

• 0.5 to 1.5 mg subcutaneously every 12 hours

Question 10

Special considerations:

Answer 10

• Onset is approximately 3-5 hours
• Duration is approximately 12 hours