Haloperidol (Haldol) Toxicologic Emergency Medication

Question 1

Classification:

Answer 1

• Antipsychotic agent

Question 2

Action:

Answer 2

• Selectively blocks postsynaptic dopamine receptors

Question 3

Indications:

Answer 3

• Psychotic disorders
• Agitation

Question 4

Adverse Effects:

Answer 4

• Extrapyramidal symptoms
• Drowsiness
• Tardive dyskinesia
• Hypotension
• HTN
• VT
• Sinus tachycardia
• QT prolongation
• Torsades de pointes

Question 5

Contraindications:

Answer 5

• Depressed mental status
• Parkinson disease

Question 6

Dosage (Adult)
Mild Agitation:

Answer 6

• 0.5 to 2 mg PO or IM

Question 7

Dosage (Adult)
Moderate Agitation:

Answer 7

• 5 to 10 mg PO or IM

Question 8

Dosage (Adult)
Severe Agitation:

Answer 8

• 10 mg PO or IM

Question 9

Dosage (Pediatric):

Answer 9

• 1 to 5 mg IM or PO for acute psychosis/agitation

Question 10

Special Considerations:

Answer 10

• IV use is considered “off label” although it is used routinely in many settings
• Consult department protocols or state/regional guidelines prior to administering
• Monitor ECG if administering IV