Fosphenytoin (Cerebyx) Seizure Medication

Question 1

Classification:

Answer 1

• Anticonvulsant

Question 2

Action:

Answer 2

• Depresses seizures by affecting the movement of sodium and calcium into neural tissue

Question 3

Indications:

Answer 3

• Generalized tonic-clonic seizures

Question 4

Adverse Effects:

Answer 4

• Depression of cardiac conduction
• Sedation
• Nystagmus
• Delirium
• Tremors
• Ataxia
• Dysarthria
• HTN
• Hypotension
• Pain/irritation at injection site

Question 5

Contraindications:

Answer 5

• Sinus bradycardia
• SA block
• Second and third degree heart block
• Adams-Stokes syndrome
• Known sensitivity to hydantoins

Question 6

Dosage (Adult and Pediatrics):

Answer 6

• Dosing is ordered in milligram phenytoin equivalents (PE) instead of mgs
• Administer 15-20 mg PE/kg IV, IO
• Administered at rate of less than 150 PE/min

Question 7

Special Considerations:

Answer 7

• Continuously monitor the ECG and BP during administration
• Monitor IV site for signs of infiltration