Hand Tumors Flashcards
Epidermal inclusion cysts in the fingertip can mimic infective or malignant conditions
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Most ganglions can be managed conservatively.
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majority oftumors that arise in the hand and wrist are benign,
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Tumors arising from the hand and wrist usually present as a painless mass
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Transillumination is an
invaluableclinical sign when assessing forganglions.
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Tumors that arise from tendons or tendon sheaths are usually mobile
sideways
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For lesions
involving the nail complex, abnormal nail pigmentation and deformity
(e.g., ridging, loss ofadherence) should be looked for.
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The main modality
for evaluating hand tumors
plain radiographs
CT scans, which provide better resolution and
three-dimensional bone anatomy, are frequently needed to augment
X-rays to properly assess bony changes
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Ultrasound is a low-cost and readily available modality that can
help to assess the nature of the mass (solid versus cystic), the vascularity, and the relative location of the mass.
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it is difficult to differentiate between benign and
malignant masses on ultrasound alone
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the main modality for imaging complex soft tissues
masses
MRI
Benefit of MRI in evaluating soft tissue ,mass
characterization of tumor activity(heterogeneouscontrast enhancement as well as perilesional edema suggesting a locally aggressive tumor).
assess response to adjuvant therapy
look for local recurrence in a surgical bed
MRI can also delineate soft tissue compartments and relationship of the mass to neurovascular structures
Nuclear medicine scans are not specific and cannot differentiate between infection, trauma, and neoplasms
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When nuclear medicine scans are coupled with
anatomical imaging such as CT and MRI scans, their utility is further
enhanced
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18-FDG positron emission tomographyscans can also help
to monitor the response to neoadjuvant treatment such as chemotherapy, and can be used as a tool to help prognosticate patients
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myxoid liposarcomas can be evaluated with 18-FDG scan
F tumors, such as myxoid liposarcomas, may not be metabolic and have low 18-FDG uptake, which will limit the utility of these scans
size should not be the only criterion to rule out malignancy
Because a majority (77%) of patients with soft tissue sarcomas present with tumors less than 5 cm in greatest dimension
majority of malignant tumors in the hand are detected when they are small
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The standard for diagnosis is biopsy
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Marginal excision is sufficient for almost all benign soft tissue tumors.
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. Wide excision, which involves excision
of the tumor through a margin of normal tissue, may be required for
some benign but locally aggressive tumors such as desmoid tumors.
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For locally aggressive bone tumors such as
giant cell tumors, local adjuvant treatment using techniques such
as cryosurgery or phenol are added to reduce local recurrence rates.
Safety margin for sarcoma excision?
For sarcomas, there is no universally agreed margin, but in
general, 1 cm of soft tissue, or an appropriate anatomic layer such as fascia, is accepted
In the hand, the margins are invariably narrow due to the closeness
of critical structures.
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What is the down side of neoadjuvant treatment
there is a risk of tumor progression during neoadjuvant treatment, and higher wound infection rates are seen in patients that have undergone preoperative
radiotherapy
Postoperative radiotherapy indication ?
should be considered for patients
following resections with close margins or microscopically positive margins
Postoperative chemotherapy can also be considered
for
selected patients with large, high-grade tumors.
The biopsy track should be excised en bloc together with the main
tumor during the definitive resection.
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Dissection should be done
through normal tissue that is not contaminated by tumor
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Critical vessels and nerves that are not grossly involved by the tumor can be preserved by dissecting through the adventitia or epineurium
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Most patients with soft tissue sarcoma loss their hand
F Hand preservation is possible for most patients with soft tissue
sarcomas of the hand, even those with relatively large tumors.
well-performed ray
amputation can result in a more functional hand thana reconstructed
digit that is painful, poorly padded, and stiff
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Functional reconstruction can be delayed until
all other treatment has been completed
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most common soft tissue tumors seen in the hand
Ganglions are the most common soft tissue tumors seen in the handthey are mucin-filled cysts and are not true neoplasms
At wich age ganglion can occur?
Ganglions
can occur at any age, though they are more commonly seen between
the second to fourth decade