Genetics and Neonatal Care Flashcards
Monohybrid Cross
Two individuals that differ for a single trait
* 1 dominant and 1 recessive gene each
Dihybrid Cross
Two individuals that differ for two traits
* 2 dominant and 2 recessive genes for each
Inheritance Patterns
Based on location of gene and whether is it dominant or recessive
* sex-linked = genes located on sex chromosomes X and Y
* autosomal = all other genes
X-Linked Recessive
Carrier Females
- Gene on X-linked chromosome
- Carrier females = unaffected
- Sons from carrier females have 1:1 chance of expressing
- Affected males will pass on to all daughters, never to sons
- Unaffected males never transmit
- ex: colorblindness
X-Linked Recessive
Males vs Females
- Males with X-linked recessive gene will always express it
- Females need to be homozygous for X-linked recessive gene to express
Backcross
Breeding
- F1 = offspring bred from two purebred parents
- Backcross = F1 bred to one with identical genes as parent
- No relation
Outbreeding
- Also called random breeding
- Helps keep gene pool as large as possible
- Breeding done between unrelated individuals
Assortative Breeding
- Breeding of those with similar genes
- Specific gene characteristics are chosen to help pass on to offspring
Inbreeding
- Breeding of closely related individuals
- Increases similarities in offspring
- Produced after 20 or more consecutive inbred matings
- Chance to express lethal genes
- Inbred depression = more poor genes begin showing
Line Breeding
System of inbreeding to guarantee similar traits in offspring
* genes chosen from one or more exceptional members of the line to pass on
Transgenic Strains
Altering of the genetic makeup of a developing embryo
Translocation
- Breakage of two chromosomes
- Repairs in abnormal arrangement
Duplication
Allele is duplicated
* ex: Down syndrome
Lethal Genes
Gene that will cause death of embryo, death after birth, or serious impairment
* semilethal = abnormal traits
* most are recessive genes
Feline
Estrous / Gestation
- Seasonally polyestrous
- Induced ovulation
- Gestation = 63 days
Canine
Estrous / Gestation
- Nonseasonal - no true cycle
- Estrus occurs twice per year
- Gestation = 63 days
Estrous Cycle
Proestrus
- Vulva swollen with discharge
- Males attracted but not accepted by female
- Noncornified squamous epithelial cells
Estrous Cycle
Estrus
- Clear discharge
- Females accept males
- Cornified squamous epithelial cells
- Ovulation 2-4 days after stage starts
- Metestrus occurs at the end, but no specific timing
Estrous Cycle
Diestrus
- Males no longer accepted
- Abrupt decrease in cornified cells towards end of estrus - become noncornified
Estrous Cycle
Anestrus
- Sexual inactivity between cycles
- Difficult to differentiate from diestrus via cytology
Equine
Estrous / Gestation
- Seasonally polyestrous - spring to autumn
- Can induce estrous by increasing light exposure
- Gestation = 335 days or 11 months
Equine
Pregnancy Determination
Transrectal Ultrasound
Q Fever
- Caused by Coxiella burnetii (rickettsial organism)
- Causes abortions
- Zoonotic from infected material
Bovine
Estrous / Gestation
- Nonseasonal Polyestrous 7-18 months
- Gestation = 278 days or 9 months
Bovine
Pregnancy Determinations
Rectal palpation and ultrasound
Bovine
Free Martin
Female twin of a male cafe
* infertile
* hermaphrodite
Brucellosis
- Causes abortions, weak kids, mastitis in goats
- Caused by Brucella spp
- Zoonotic - causes Malta fever in humans
- Shed via body secretions
Caprine
Estrous / Gestation
Goats
* seasonally polyestrous - fall and winter
* induced estrous with light manipulation
* gestation = 149 days
Caprine
Estrous Cycle Control
- Buck effect - bring male with odor to female
- Prostaglandins = induce ovulation
- Progestins = delay ovulation
Ovine
Estrous / Gestation
Sheep
* seasonally polyestrous - fall and winter
* can induce va light manipulation
* gestation = 145-155 days or 5 months
Ovine
Estrous Control
- Whitten Effect - ram introduced just before breeding season to jump start cycle
- Flushing - increased dietary intake
Porcine
Estrous / Gestation
Pigs
* nonseasonal polyestrous
* gestation = 114 days or 3 months, 3 weeks, 3 days