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Pharm > First aid drugs test 3 > Flashcards

First aid drugs test 3 Flashcards

1
Q

What is the MOA of ethosuximide, and what is it used to treat?

A

Ca channel blocker

Absence seizures

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2
Q

What is the MOA of benzodiazepines as antiepileptics? What type of seizures are these used to treat? Which of the two benzos are used to treat this?

A

GABA-(A) agonists
Treats status epilepticus
Diazepam and lorazepam

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3
Q

What is the MOA of phenytoin? What type of seizures is it used to treat?

A

Na channel blocker

Simple, complex, tonic/clonic, and status epilepticus

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4
Q

What is the MOA of carbamazepine? What type of seizures is it used to treat?

A

Na channel blocker

Simple, complex, and tonic clonic

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5
Q

What is the MOA of valproic acid? What type of seizures is it used to treat?

A

Na channel blocker and GABA transaminase inhibitor

Simple, complex, tonic clonic, and absent

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6
Q

What is the MOA of gabapentin? What type of seizures is it used to treat?

A

Ca channel blocker

Simple, complex, tonic/clonic

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7
Q

What is the MOA of phenobarbital? What type of seizures is it used to treat?

A

Increase GABA-(A) channel open duration

Simple, complex, tonic/clonic

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8
Q

What is the MOA of Topiramate? What type of seizures is it used to treat?

A

Na channel blocker

simple, complex, tonic/clonic

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9
Q

What is the MOA of Lamotrigine? What type of seizures is it used to treat?

A

Na channel blocker

All szs except tonic/clonic

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10
Q

What is the MOA of Tiagabine? What type of seizures is it used to treat?

A

Inhibit GABA reuptake

Simple and complex seizures

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11
Q

What is the MOA of Vigabatrin? What type of seizures is it used to treat?

A

Irreversible inhibitor of GABA transaminase

simple and complex

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12
Q

What are the drugs used to treat simple seizures? Complex?

A

All antiepileptics except ethosuximide and benzos

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13
Q

What are the drugs used to treat tonic/clonic seizures?

A

All antiepileptics except Ethosuximide, Benzos, tiagabine and vigabatrin

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14
Q

What are the drugs used to treat absence seizures (3)?

A

Ethosuximide
Valproic acid
Lamotrigine

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15
Q

What are the drugs used to treat status epilepticus (2)?

A

Benzos

Phenytoin

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16
Q

Chlorpromazine

A

Typical antipsychotic

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17
Q

Thioridazine

A

Typical antipsychotic

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18
Q

Fluphenazine

A

Typical antipsychotic

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19
Q

Haloperidol

A

Typical antipsychotic

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20
Q

Clozapine

A

Atypical antipsychotic

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21
Q

Olanzapine

A

Atypical antipsychotic

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22
Q

Risperidone

A

Atypical antipsychotic

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23
Q

Aripiprazole

A

Atypical antipsychotic

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24
Q

Quetiapine

A

Atypical antipsychotic

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25
Q

Ziprasidone

A

Atypical antipsychotic

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26
Q

What is the MOA and use of: Moclobemide

A

MAO-A inhibitor

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27
Q

What is the MOA and use of: memantine

A

Ca channel blocker, Glutamate inhibitor (NMDA antagonist to treat AD

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28
Q

What is the MOA and use of: Meprobamate

A

Sedative given prior to surgery (Benzo-like)

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29
Q

What is the MOA and use of: Ropinirole

A

Dopamine receptor agonist used in the treatment of Parkinson’s

30
Q

What is the MOA and use of: Amantadine

A

antiviral given for PD. Unknown MOA

31
Q

What is the MOA and use of: Trihexyphenidyl

A

M2 blocker used for the treatment of Parkinson’s treatment

32
Q

What is the MOA and use of: Pramiprexole

A

Dopamine receptor agonist used in PD

33
Q

What is the MOA and use of: Apomorphine

A

Dopamine receptor agonist used in PD when L-DOPA doesn’t work anymore

34
Q

What is the MOA and use of: Rasagiline

A

MAO-B inhibitor for PD

35
Q

What is the MOA and use of: Atomoxetine

A

NE reuptake inhibitor used in the treatment of ADHD

36
Q

What is the MOA and use of: Modafinil

A

Histamine receptor agonist used to increase wakefulness in epileptic patients

37
Q

What is the MOA and use of: Pentylenetetrazol

A

GABA-(A) antagonist used as a respiratory stimulant

38
Q

What is the MOA and use of: Fomepizole

A

Alcohol dehydrogenase inhibitor, used in the treatment of methanol ingestion

39
Q

What is the MOA and use of: Disulfram

A

Acetaldehyde dehydrogenase inhibitor, used in the treatment of alcoholism d/t causing adverse side effects of acetaldehyde buildup (N/v, flushing)

40
Q

What is the MOA and use of: Retigabine

A

Potassium channel opener, anticonvulsant

41
Q

What is the MOA and use of: Mirtazapine

A

Alpha-2 antagonist used in the treatment of depression, causing increased release of catecholamines

42
Q

What is the MOA and use of: Felbamate

A

Na and Glutamine antagonist used for anticonvulsant

43
Q

What is the MOA and use of: Topiramate

A

Anticonvulsant

Na and Ca channel blocker, potentiates GABA

44
Q

What is the MOA and use of: Benztropine

A

M receptor antagonist used in PD

45
Q

What is the MOA and use of: Duloxtine

A

SNRI, depression and chronic pain

46
Q

What is the MOA and use of: Trazodone

A

5HT2 antagonist, hypnotic

47
Q

What are the two anticonvulsants used to treat myotonic seizures?

A

Clonazepam

Valproic acid

48
Q

What is the sedative that can be used safely in pregnant women

A

Phenobarbital

49
Q

What is the MOA and use of: Primidone

A

Converted into phenobarbital in the liver (sedative)

50
Q

What is the major adverse reaction with halothane

A

Hepatitis

51
Q

What are the advantages and disadvantages of sevoflurane

A

Fast onset, potent, not as irritating to the lungs

Kidney and hepatic damage

52
Q

What is the major downside of propofol

A

Decreased CO

53
Q

What is the major downside of Enflurane

A

CNS stimulant

Pungent odor

54
Q

What are the two pungent Halogenated agents?

A

Enflurane

Isoflurane

55
Q

Which halogenated agent should not be given to a pt with a h/o smoking or COPD? Why?

A

Desflurane

Airway irritant

56
Q

What is the ideal halogenated agent?

A

Sevoflurane

57
Q

Which opioid analgesic has a severe reaction with MAOIs? Why?

A

Meperidine–5HT reuptake inhibition will cause serotonin syndrome

58
Q

Which type of local anesthetic produces PABA as a byproduct?

A

Esters

59
Q

Which two atypical antipsychotics are associated with weight gain?

A

Clonazapine

Olanzapine

60
Q

Which atypical antipsychotic causes tardive dyskinesia?

A

Risperidone

61
Q

Which type of antipsychotics have more active metabolites: Typical or atypical

A

Atypical

62
Q

Which amino acids interfere with L-DOPA absorption?

A

Leucine and isoleucine

63
Q

Short, medium, or long acting: triazolam

A

Short

64
Q

Short, medium, or long acting: lorazepam

A

Medium

65
Q

Short, medium, or long acting: oxazepam

A

Medium

66
Q

Short, medium, or long acting: temazepam

A

Medium

67
Q

Short, medium, or long acting: alprazolam

A

Medium

68
Q

Short, medium, or long acting: Clorazepate

A

Long

69
Q

Short, medium, or long acting: Diazepam

A

Long

70
Q

Short, medium, or long acting: Chlordiazepoxide

A

Long

71
Q

Short, medium, or long acting: flurazepam

A

Long

Pharm (73 decks)

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