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Pharm > Extra > Flashcards

Extra Flashcards

1
Q

What are the vehicles for dry skin?

A
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2
Q

What are the vehicles for wet skin?

A
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3
Q

What is benzoyl peroxide usually used in combination with? Why?

A

Abx–no resistance with benzoyl peroxide

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4
Q

What is the difference between azelaic acid and salicylic acid?

A

Azelaic acid is antibacterial

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5
Q

What is the difference between isotretinoin and the other retinoids?

A

Apoptosis of sebum cells

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6
Q

Which drug that treats psoriasis has a super long half life, and can cause teratogenic effects long after, especially combined with EtOH?

A

Acitretin

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7
Q

What is the MOA of calcipotriene?

A

Inhibit IL2 and IL6 production, and inhibits proliferation of keratinocytes

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8
Q

What is the major keratolytic drug?

A

Salicylic acid

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9
Q

Why is diphenhydramine used with antipsychotics?

A

Reduces EPS ssx

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10
Q

What is phenergan? MOA?

A

Promeclazine 1st gen antihistamine

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11
Q

What are the second generation antihistamines?

A 
Fexofenadine
Loratadine
Desloratadine
Cetirizine
Levocetirizine
Azelastine
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12
Q

What should never be given with fexofenadine?

A

CYP inducers

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13
Q

What are the three mast cell stabilizers?

A

Cromolyn
Nedocromil
Omalizumab

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14
Q

What is the MOA of Omalizumab? What is this used for?

A

binds to IgE, preventing mast cell degranulation

Used for chronic urticaria

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15
Q

What is doxepin used for?

A

Used for chronic urticaria

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16
Q

What is the MOA of ketotifen?

A

Mast cell and basophil used for ophthalmic

17
Q

What cause the HTN seen with ketoconazole use?

A

Shunting of cholesterol down the aldosterone synthesis pathway

18
Q

What is the advantage of methyltestosterone? Major adverse effect?

A

Can be taken orally

Hepatotoxic

19
Q

How is testosterone ethanate given?

20
Q

How is Testosterone administer?

A

Transdermally

21
Q

What is the MOA (x3) of enzalutamide?

A
  1. Competitive inhibitor of androgen receptor
  2. Inhibit translocation of the AR into the nucleus
  3. Inhibits AR binding to DNA
22
Q

What is the MOA of Degarelix?

A

GnRH receptor Antagonist

23
Q

What is the MOA of abiraterone? Side effects?

A

blocks 17alpha

Decreased cortisol, increased aldosterone

24
Q

What is the MOA of finasteride and dutasteride?

A

Blocks 5-alpha reductase

25
Q

What do you pretreat ***

26
Q

What is the suffix for PDE5 inhibitors?

A

denafil or dalafil

27
Q

What are the three short acting insulins?

A

Lispro
Aspart
Glulisine

28
Q

What are the two long acting insulins?

A

Glargine

Detemir

29
Q

What is the intermediate form of insulin?

Pharm (73 decks)

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