Final Exam Chapter 6 review Flashcards
What is cAMP and the function of it?
acts as a crucial “second messenger” molecule, transmitting signals from extracellular hormones or neurotransmitters to the inside of a cell, thereby regulating a wide range of cellular functions
What are two ways calcium enters the cytosol of a cell in signal transduction?
- Release of stored Calcium in the Smooth plasmic reticulum (SER), and Endoplasmic reticulum (ER)
- Opening of calcium channels
When does calcium become a second messenger?
- When it is released to the inside of the cell. And when it binds to the calmodulin which activates other enzymes
Name two triggers/mechanisms that stimulate an increase of intracellular calcium
- G proteins: which triggers the SER to release a lot of Ca2+
- Phospholipase C: Which phosphorylates calcium channel proteins. Which opens the channels and permits extracellular calcium to come in
What does the second messenger do in signal transduction?
alters the gating of ions, increases intracellular calcium levels, and changes enzyme activity
What is osmosis?
moving from low solute concentration to high solute concentration
What is the job of the G-protein coupled receptor?
When a ligand binds to it, It acts as a middleman between the receptor and second messenger which can open an ion channel or alter enzyme activity
What is the role of the G-protein coupled receptor in signal transduction?
It is a second messenger in signal transduction which can open an ion channel or alter enzyme activity
What is the pathway of the first messenger epinephrine and norepinephrine that uses cAMP as a secondary messenger (4 steps) DONT KNOW SPECIFICS JUST GET THE MAIN CONCEPT OF IT
- It binds to the protein receptor
- G protein is activated and activates enzyme Adenylate Cyclase
- Adenylate cyclase converts ATP to cAMP (amplifies ATP to do that)
- camp is a second messenger and induces enzyme activity and releases glucose in the skeletal muscles and liver