Final Exam Chapter 6 review Flashcards

1
Q

What is cAMP and the function of it?

A

acts as a crucial “second messenger” molecule, transmitting signals from extracellular hormones or neurotransmitters to the inside of a cell, thereby regulating a wide range of cellular functions

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2
Q

What are two ways calcium enters the cytosol of a cell in signal transduction?

A
  1. Release of stored Calcium in the Smooth plasmic reticulum (SER), and Endoplasmic reticulum (ER)
  2. Opening of calcium channels
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3
Q

When does calcium become a second messenger?

A
  • When it is released to the inside of the cell. And when it binds to the calmodulin which activates other enzymes
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4
Q

Name two triggers/mechanisms that stimulate an increase of intracellular calcium

A
    1. G proteins: which triggers the SER to release a lot of Ca2+
    1. Phospholipase C: Which phosphorylates calcium channel proteins. Which opens the channels and permits extracellular calcium to come in
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5
Q

What does the second messenger do in signal transduction?

A

alters the gating of ions, increases intracellular calcium levels, and changes enzyme activity

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6
Q

What is osmosis?

A

moving from low solute concentration to high solute concentration

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7
Q

What is the job of the G-protein coupled receptor?

A

When a ligand binds to it, It acts as a middleman between the receptor and second messenger which can open an ion channel or alter enzyme activity

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8
Q

What is the role of the G-protein coupled receptor in signal transduction?

A

It is a second messenger in signal transduction which can open an ion channel or alter enzyme activity

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9
Q

What is the pathway of the first messenger epinephrine and norepinephrine that uses cAMP as a secondary messenger (4 steps) DONT KNOW SPECIFICS JUST GET THE MAIN CONCEPT OF IT

A
  1. It binds to the protein receptor
  2. G protein is activated and activates enzyme Adenylate Cyclase
  3. Adenylate cyclase converts ATP to cAMP (amplifies ATP to do that)
  4. camp is a second messenger and induces enzyme activity and releases glucose in the skeletal muscles and liver
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