Exam 1 - FA Asymmetrical Brain Disease Flashcards
what is the hallmark sign of listeria infection?
multifocal cranial nerve signs with depression & acute onset
how does a listeria infection occur?
stored silage is disturbed & spoils (dirt/moisture is allowed in), pH goes up & bacteria multiplies
what is the pathophysiology of listeria monocytogens?
enters via mucus membranes of mouth or conjunctiva or nares & migrates centripetally up the trigeminal nerve
what animals are commonly affected by listeria?
cattle, sheep, & goats
what animals commonly get listeria probs during tooth eruption?
cows
what is the environment that is favorable for listeria?
pH > 5.5, oxygen supply, & good moisture
lives in the soil, vegetation, & fecal material (spoiled silage)
what deficits are seen from listeria in regards to the trigeminal nerve?
loss of sensation to the face & dropped jaw on the same side of the lesion
what deficits are seen from listeria in regards to the abducens nerve?
medial strabismus
what deficits are seen from listeria in regards to the facial nerve?
droopy lip, droopy eye, secondary keratitis, deviated nares
what deficits are seen from listeria in regards to the vestibulocochlear nerve?
head tilt
what deficits are seen from listeria in regards to the glossopharyngeal & vagus nerves?
dysphagia & salivation - may lead to acidosis
what deficits are seen from listeria in regards to the hypoglossal nerve?
decreased tongue tone
how is a listeria infection diagnosed?
clinical signs/history
CSF - increased monocytes & proteins = MONONUCLEAR PLEOCYTOSIS
illness > 4 days - usually excludes rabies
what is the zoonotic potential of listeria?
organisms in milk may withstand pasteurization!!
what is seen postmortem in listeria?
multifocal micro-abscesses in the brain
