Exam 1: Antigens Flashcards
Molecules that induce an immune response when introduced into the body
antigens
What are the two subcategories of antigens
- immunogens
2. haptens
Subcategory of antigens that are capable of stimulationg an immune response
Immunogens
Subcategory of antigens that will not by themselves stimulate an immune response but can do so when complexed with a larger molecule
Haptens
What are the two cardinal features of antigens
Immunogenicity and antigenicity
Antigens are capable of inducing an immune response
Immunogenity
Antigens are capable of binding with products of the immune response that they induced
Antigenicity
Part of the antigen responsible for inducing the immune response and binding to the products of the immune response.
Epitope
What 7 factors affect immunogenicity of antigens
- foreignness
- size
- Chemical composition
- Physical properties
- Degradability
- genetic factors
- age
T/F. The smaller the antigen the more immunogenic it can be.
F. Larger= more immunogenic
Substance that enhances the body’s immune response to an antigen
Adjuvant
What are the 5 types of antigens?
- T-independent antigens
- T-dependent antigens
- superantigens
- Haptens
- Autoantigens
Type of antigens that directly stimulate b lymphocytes without the need of helper t cells
T- independent antigens
What is an example of a t independent antigen
Lipopolysaccharides
Type of antigen that indirectly stimulate B cells to produce antibodies
T-dependent
