Endocardite Flashcards

1
Q

Ce contine vegetatia

A

Fibrina
Microorganisme
Trombocite
Cel infl

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2
Q

Unde apare vegetatia

A

Sept
Endocard
Cordaje
Valve

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3
Q

Factori predispozanti vegetatie

A

Proteze valvulare
Abuz droguri
Scleroza valvulara defenerativa
Profeduri invazive

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4
Q

Dupa modalitatea de dobandire endicardita e

A

Dobandita in comunitate
Nosocokial sau nonnosicimial
Abuz droguri iv

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5
Q

Endocardita activa

A

Febra sau hemoculturi poz
Morfologie inflamatorie la operatie
Pacient sub terapie antibiotica
Histopat

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6
Q

Microbiologie endocardita

A

Hemoculturi pozitive STAF STREPTO ENTERO
hemocult negativ: a luat antib, brucella, fungi, HACEK hemofilus, actinobacilus, cardiobacterium, eikenela, kingela
+coxiela clamidia bartonela

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7
Q

Fizpat endocardita

A
Leziune sau nu a endocardului
Tbocite si fibrina
Vegetatie sterila
Bacteriemie
Vegatatie
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8
Q

Suspiciune clinica endocardita

A

Sufluri de regurgitare noi(e ca un fel de prolaps) sau noi tulburari de conducere

Evenimente embolice cu orig necunoscuta

Sepsis cu orig nrcunoscuta

FEBRA!!! Poate lipsi la batrani imunocompromisi

Frisoane anorexie scadere ponderala

Boala valvulara sau cardiaca preexistenta

Interventii recente

Evidenta insuf cardiaca

Pete roth hemoragii subunghiale lez janeaway noduli osler

Embolie pulmonara abces periferice

Culturi pozitive sau febra q

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9
Q

Clinic endocardita

A

Artrita mialgii artrite
Simptome neurologice
Insuficienta renala(gnf, infracte, medicamente nefrotixice)

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10
Q

Diagnostic endocardita

A
Anemie
Leucocitoza
Probe inflamatorii
Factor reumatoid
TEE-prima intentie
TTE
CT
Rmn lez cerebrale

HEMOCULTURI nu se asteapta puseu febril
Anatomopat
Histologic
Pcr

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11
Q

Criterii duke

A

Criterii patologice microorg femonstrat prin cultura sau histopat
Lez pat vegetatii sau abcese

Criterii majore:
Eco pozitiv
Activitate anormala in jurul protezei
Henoculturi po

Criterii minore
Conditii cardiace favorizante
Febra
Fenomene vasculare
Fen imunologice
Probe microbiologice care nu intrunesc criteriile majore
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12
Q

Evaluare prognostic

A
Varstnic
Endocardita pe proteza
Dz imunodep
Comorbiditati boala pulm, renala, imunosupresie
Prezenta complicatii
Microorganism staf fungu bgn
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13
Q

Tratament endocardita

A

Terapia or proteze dureaza mai mult

Streptococ: penicilina g sau amoxi sau ceftriaxona +-gentamicina si netilmicina sau vancomicina

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14
Q

Evaluare eficienta terapie

A

Apirexie
Hemoculturi negative dupa 3-4 z
Normalizare leucocite
Teste de inflamatie

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15
Q

Chirurgie endocardita

A

1 insuf cardiaca
2 infectie necontrolata: local(abces, pseudoanevrism, fistula, veg mare)/ hemoculturi persistente/fungi/pve)
3 preventia embolismului

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16
Q

Tipuri endocardita

A

Stamga(pe valve native, valve pritetice natuv sau tardiv)
Dreapta
In rel cu dispozitive(pacemaker, defibrilator)

17
Q

Endocardita recurenta 2 tipuri

A

Recadere <6 luni

Reinfectie

18
Q

Dg clinic endocardita

A

Artralgii mialgii artrite

Simpt neurologice(avc embolic, hemoragii intracraniene, encefalita, miningita, cefalee, convulsii)

Ir: gnf, infarcte, medicatie

19
Q

Dg teste lab endocardita

A

Anemie normo normo hiposideremica(poate lipsi in acut)

Leucocitoza cu neutrofilie

Vsh, fibrinogen, pcr

Freumatoid

Cic, complement scazut

Proteinurie hematurie

20
Q

Dg imagistic endocardita

A

Tte!!!!!!!!!!!!!!!
Tee daca tte e normala si suspiciunea inalta
Se repeta in7-10 zile
Se repeta daca sunt suspectate noi complicatii
La sf terap antibiotice

Ct multislice
Detectie abcese, extensie perivalulara, angiografie, leziuni cerebrale

Rmn pt cerebrale

Spect si oet dau imfirmatii suplimentare

21
Q

Dg microbiologic

A

Hemoculturi
Exam anatomopatologica
Tehnici histologice
Pcr

22
Q

Criterii duke

A
Dg definitiv in prezenta a:
Crit patologice( microorg demonstrat prin cultura sau examen histopatologic a vegetatiei, embolului, abcesului; lez oatologice confirmate histologic)
Criterii clinice(2 majore /1 major 3 minore/5 minore)

Dg posibil 1 major si 1 minor sau 3 minor

Dg exclus ag alternativ ferm, rezolutie simot dupa atb<4 zile, fara evidenta de ei la chir, nu intruneste criterii

23
Q

Criterii majore endocardita

A

Img pozitiva(eco pozitiv/// activitate anormala in jurul protezei prin pet sau spect///les paravalvulara la ct)

Hemoculuri- cu microorg tipice minim 2 culturi sau compatibile dinhemoculturi permanent persistente

24
Q

Criterii minore e dicardita

A

Cond cardiace favorizante
Injectare droguri
Febra
Fenomene vascukare(embolii, infarte, anevrisme, hemoragii intracraniene, lez janeway, hemoragii conjunctivale)
Fenomene imunologice(gm, osler, pete roth, fr)
Hemoculturi care nu intr criteriile majore

25
Q

Prognostic la internare

A

Varstnic ei pe proteza dz insulinonecesitant comorbiditati

Complicatii(ic, avc, ir, perianular, soc septic)

Microorganism(s auriu, fungi, bgn)

Compl perianulare, reg valvulare stangi
Fe scazuta
Htap
Vegetatii mari, disf protetica
Inchidere orematura vm sau alte semne de crestere a pres diastolica
26
Q

Atb pt streptococ si bovis

A

Penicilina g
Amoxicilina
Cefriaxona

Gentamicina

Daca au alergie la betalactami-vancomicina

27
Q

Evaluare terapie endocardita

A

Apirexie
Hemoculturi neg dupa 3-4 z
Leucocite normalizare(grija ca vencomicina da neutropenie)
Teste inflamatie:vsh(scade ultimul), fibrinogen, pcr, procalcitonina(scade prima)

28
Q

Chirurgie valve endocardita

A

Ic care da in epa sau echo de toleranta scazuta hemodin

Infectie necontrolata local, fungi sau bact multirez, hemoculturi persisten pozituve, PVE(?) data de stafilococ su bgn

Preventie embolism(vegetatii mari+- stenoza severa valvulara, sau vegetatie f mare)