CP: Chapter 5 Mood Disorders Flashcards

1
Q

mood disorders =

A

disorders that involve depressive or manic symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

major depressive disorder DSM

A

either (1) depressed mood or (2) loss of interest or pleasure.

  1. insomnia or hypersomnia
  2. weight loss or gain
  3. concentration issues or indecisiveness
  4. psychomotor agitation (a state of restlessness and anxiety that results in repetitive and unintentional movements) or retardation (slowing down of thought and a reduction of physical movements in an individual).
  5. fatigue
  6. feelings of worthlessness
  7. thoughts of death

at least 5, at least 1 or 2, and for a period of 2 weeks

B. symptoms should cause distress/impairment
C. not due to medication or other disorder
D. not better explained by schizoaffective disorders
E. never a manic/hypomanic episode (excl. die tijdens medicatie of door andere disorder)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The diagnostic code for major depressive disorder is based on whether this is a ….

A

recurrent?
severity?
psychotic?
remission?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

remission =

A

beter voelen, meestal na een MDD episode.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

persistent depressive disorder DSM

A

A. depressed mood for most of the days, for at least 2 years.
(one year in children and adolescents, + here the mood may be irritability)

B. 2 van de volgende symptomen:
1. Poor appetite or overeating.
2. Insomnia or hypersomnia.
3. Low energy or fatigue.
4. Low self-esteem. (anders dan MDD!)
5. Poor concentration or difficulty making decisions.
6. Feelings of hopelessness.

C. nooit meer dan 2 maanden zonder de symptomen geweest
D. Criteria for a major depressive disorder may be continuously present for 2 years.
E. never manic
F. no schizophrenia/psychosis
G. not due to substances or other disorder
H. symptoms cause distress/impairment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

persistent depressive disorder is een combinatie van…

A

chronic major depressive disorder and dysthymic disorder.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

If criteria are met for both major depressive disorder and
persistent depressive disorder, both can be diagnosed.

A

oke

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

disruptive mood dysregulation

A

A. temper outbursts (verbal or physical)
B. temper is inconsistent with developmental level
C. temper; 3 or more times per week
D. mood during temper is irritated or angry, and observed by others
E. criteria a-d meer dan 12 maanden, en gedurende die tijd niet meer dan 3 maanden weg
F. a-d present in at least 2 settings (at school/home/peers) and at least one of them was severe
G. diagnosis: between 6 and 18 years old
H. meestal voor age of 10
I. nooit criteria voor hypo/mania
J. The behaviors do not occur exclusively during an episode of major depressive disorder and are not better explained by another mental disorder (e.g., autism spectrum disorder, posttraumatic stress disorder, separation anxiety disorder, persistent depressive disorder).
K. nooit door substances, medication of andere medical condition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

premenstrual dysphoric disorder

A

A. In the majority of menstrual cycles, at least five symptoms must be present in the final week before the onset of menses, start to improve within a few days after the onset of menses, and become minimal or absent in the week postmenses.

B. at least one:
1. Marked affective lability (e.g., mood swings; feeling suddenly sad or tearful, or increased sensitivity to rejection).
2. Marked irritability or anger or increased interpersonal conflicts.
3. Marked depressed mood, feelings of hopelessness, or self-deprecating thoughts.
4. Marked anxiety, tension, and/or feelings of being keyed up or on edge.

C. One (or more) of the following symptoms must additionally be present, to reach a total of five symptoms when combined with symptoms from B above.
1. Decreased interest in usual activities (e.g., work, school, friends, hobbies).
2. Subjective difficulty in concentration.
3. Lethargy, easy fatigability, or marked lack of energy.
4. Marked change in appetite; overeating; or specific food cravings.
5. Hypersomnia or insomnia.
6. A sense of being overwhelmed or out of control.
7. Physical symptoms such as breast tenderness or swelling, joint or muscle pain, a sensation of “bloating,” or weight gain.

D. symptoms cause distress/impairment
E. not other disorders
F. should be confirmed by daily ratings(but: The diagnosis may be made provisionally prior to this confirmation.)
G. not due to substances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

mdd men vs women

A

women 3 : men 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

mdd poor vs rich people

A

poor people: 3x more likely

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

minorities vs people who were born in USA

A

minorities: less MDD than people who were born there

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

bipolar disorder 1 most important criteria =

A

mania

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

bipolar disorder 2 most important criteria

A

major depressive episode

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

mania =(A)

A

A distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnormally and persistently increased activity or energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how long should mania last

A

lasting at least 1 week and present most of the day, nearly every day (or any duration if hospitalization is necessary).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

B criterima mania

A

3 van deze:

  1. Inflated self-esteem or grandiosity.
  2. Decreased need for sleep
  3. talkative
  4. Flight of ideas
  5. Distractibility
  6. Increase in goal-directed activity (either socially, at work or school, or sexually) or psychomotor agitation (i.e., purposeless non-goal-directed activity).
  7. Excessive involvement in activities that have a high potential for painful consequences
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

hoeveel manic episodes voor bipolar 1 diagnosis

A

at least one in lifetime

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

hypomanic A criteria

A

A distinct period of abnormally and persistently elevated, expansive, or irritable mood and abnormally and persistently increased activity or energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

hypomania hoelang moet het duren?

A

lasting at least 4 consecutive days and present most of the day, nearly every day.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

hypomania B criteria

A

3 van deze:

  1. Inflated self-esteem or grandiosity.
  2. Decreased need for sleep
  3. talkative
  4. Flight of ideas
  5. Distractibility
  6. Increase in goal-directed activity (either socially, at work or school, or sexually) or psychomotor agitation (i.e., purposeless non-goal-directed activity).
  7. Excessive involvement in activities that have a high potential for painful consequences
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

differences mania and hypomania

A

mania = one week
hypomania = 4 dagen

mania = severe, impairs functioning
hypomania = can still function normally =unequivocal change in functioning). but still noticable by others!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

wat als iemand psychotic features heeft bij bipolar?

A

per definition = manic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

hypomania in bipolar 1?

A

Hypomanic episodes are common in bipolar I disorder but are not required for the diagnosis of bipolar I disorder.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

bipolar disorder 1 criteria

A

at least one manic episode, not explained by other disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

3 reasons why we sometimes misdiagnose bipolar disorder 1 as unipolar depression/MDD

A

1) the first episode of bipolar disorder is often depressive, 2) depressive symptoms are the most frequent symptoms experienced across the long-term course of bipolar I disorder
3) the problem for which individuals typically seek help is depression.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

globaal bipolar 2 criteria

A

een past or current hypomania episode, een pas or current MDD episode

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

manic episode in bipolar 2 ?

A

bestaat niet! manic episode = altijd bipolar 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

cyclothymic disorder

A

periods with hypomanic symptoms (do not meet criteria for mania) mixed with periods of depressive symptoms (do not meet criteria MDD)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

how long should cyclothymic disorder last

A

at least 2 years (1 year for children and adolescents)
symptoms do not go away for more than 2 months at a time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

which is more prevalent: bipolar 1 or mdd?

A

mdd

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

hard to estimate the prevalence of bipolar 2, why?

A

because milder forms are hard to detect with diagnostic interviews

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

what is observed age of onset of bipolar spectrum disorders

A

usually before age of 25.
prevalence is increasing amongst children and adolescents!

34
Q

what are the most severe consequences of bipolar

A

unemployment, suicide and high risk of other medical conditions

35
Q

subtypes of depressive and bipolar disorders

A

anxious distress
mixed features
rapid cycling
peripartum onset
seasonal pattern
mood-congruent psychotic features
mood-incongruent psychotic features
catatonic features
melancholic features
atypical features
suicide risk severity

36
Q

seasonal pattern

A

episodes happen regularly at a particular time of the year

37
Q

rapid cycling

A

at least four episodes within the past year

38
Q

mood-congruent psychotic features

A

delusions/hallucinations that are consistent with the mood state

39
Q

mood-incongruent psychotic features

A

delusions or hallucinations with themes that do not match the valence of the depressive or manic episode

eg. believing you have superpowers despite going through a major depressive episode

40
Q

mixed features

A

at least 3 manic episodes during a depressive episode, or at least 3 depressive symptoms during a manic episode

41
Q

catatonic features

A

extreme immobility or excessive movement

42
Q

melancholic features

A

lack of pleasure, no relief, and at least 3 other symptoms of depression

43
Q

atypical features

A

symptoms that are unusual for manic/depressive state

44
Q

with anxious distress

A

with anxiety

45
Q

suicide risk severity

A

suicidal ideation

46
Q

is bipolar heritable

A

yes, strongly

47
Q

is depression heritable

A

somewhat

48
Q

which neurotransmitters are affected in mania and depression

A

serotonin: diminished sensitivity
dopamine: decreased sensitivity bij dep, increased sensitivity bij mania

49
Q

how does dopamine relate to mania and depression

A

mania: higher sensitivity
depression: lower sensitivity

50
Q

which brain structure is related to bipolar disorder

A

amygdala (assessing how emotionally important a stimulus is), hogere activiteit
subgenual anterior cingulate (voor emotion regulation), lagere activteit
striatum (rewards!!), hogere activiteit (deze is juist lager in depression)

51
Q

hpa axis in depression

A

hogere activiteit = minder suppression of cortisol = meer stress = depression

52
Q

which social factors are risk factors for depression

A

low social support
high expressed emotion
high need for reassurance (-> rejection -> lead weer tot meer depressie)
poor social skills

53
Q

neuroticism leidt tot meer..

A

depression and anxiety

54
Q

becks theory of depression

A

acquired negative schemas in childhood -> unconscious set of beliefs -> cognitive biases to process info in negative ways -> overly attentive to negative feedback

55
Q

hopeless theory

A

expectation that desirable outcomes will never occur, person has no resources to change this. their attributional style leads them to believe that negative life events are due to stable and global causes, zelf geen invloed op -> hopelessness -> depression

56
Q

rumination theory

A

tendency to dwell on sad experiences and thoughts may increase risk of depression

57
Q

2 predictors of mania

A
  1. reward sensitivity: mania reflects disturbances in reward sensitivity. -> live event dat leidt tot success -> confidence -> exscessive goal persuit -> mania (bij mensen met biological predisposition)
  2. sleep deprivation
58
Q

3 treatments for depression

A

interpersonal psychotherapy
cognitive therapy
behavioural activation therapy

59
Q

interpersonal psychotherapy

A

focuses on improving relationships. very social.

It addresses current problems and relationships rather than childhood or developmental issues. Therapists are active, non-neutral, supportive and hopeful, and they offer options for change.

60
Q

cognitive therapy

A

altering maladaptive thought patterns, change opinions about the self, congitive restructuring.

61
Q

adaptation of CT to prevent relapse

A

mindfulness-based cognitive therapy MBCT

62
Q

behavioural activation therapy

A

increasing participation in positively reinforcing activities, to disrupt the cycle of depression.

63
Q

difference CT and BA-T

A

BA-T is a subcategory of CT. Behavioral activation is as effective as and less costly than cognitive behavioral therapy (CBT) for patients with depression.

64
Q

3 therapies for bipolar disorder

A

psychoeducation
family focused therapy
cognitive therapy

65
Q

psychoeducation

A

help people learn about symptoms of the disorder, expected time course of symptoms, biological and psychological triggers, treatment strategies

66
Q

family focused therapy

A

educate family about disorder, enhance communication, develop problem solving skills

67
Q

3 therapies for bipolar disorder

A

psychoeducation
family focused therapy
cognitive therapy

68
Q

ECT wordt veel gebruikt voor…

A

depressie (voltage, inducing momentary seizure and unconsciousness)

69
Q

medications for depression

A

SSRI, monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants.

populairste = ssri, minste bijwerkingen

70
Q

TMS for depression

A

increase activity in the brain! (bv delen die onderactiviteit laten zien bij depressie)
aantal mensen werkt het voor, voor mensen die geen goede werking van antidepressiva hadden.

ook gebruikt voor OCD

71
Q

hoeveel % gaat de efficacy omhoog na combinatie AD en PT

A

10-20%

72
Q

verschil in effect ad en psychotherapy

A

ad: immediate relief, maar geen oplossing
pt; kan langer duren, learn skills that protect against recurrence

73
Q

medications for bipolar disorder

A

lithium
anticonvulsants
antipsychotic medication
mood stabilizers voor mensen die lithium niet aankunnen

74
Q

suicide psych disorders relatie?

A

meeste mensen die suicide plegen hebben een disorder, of which more than half have depression

75
Q

suicide heritable?

A

deels wel ja

76
Q

biologische deel van suicide

A

serotonin, overactivity of the HPA, minder dopamine, downregulation of glutamate, abnormal cortisol

77
Q

social risk factors suicide
dus wereldwijd

A

social isolation
celebrity suicides
economic recessions

78
Q

psychological risk factors suicide

A

poor problem solving
hopelessness
lack of reasons to live
impulsivity

79
Q

how to prevent suicide

A

treating mental illnesses
treating suicidality directly
CBT can help suicidal ideation

80
Q

verschillen persistent depressive disorder en major depressive disorder

A

pdd = 2jaar
mdd = 2 weken

pdd = low self esteem
mdd= psychomotor agitation or retardation, worthlessness, thoughts bout death