CORTEXT: Rheumatology

Question 1

what does arthropathy mean?

Answer 1

disease of a joint

Question 2

what does arthritis mean?

Answer 2

inflammation of the joint

Question 3

what does arthralgia mean?

Answer 3

pain in the joint

Question 4

most common type of non-inflammatory arthritis?

Answer 4

osteoarthritis

Question 5

name the 5 seropositive arthritises?

Answer 5

RA
lupus
scleroderma
vasculitis
sjogren's

Question 6

name the 4 seronegative arthritises?

Answer 6

ankylosing spondylitis
psoriatic arthritis
reactive arthritis
IBD arthritis

Question 7

what is meant by a seropositive condition?

Answer 7

autoantibodies present in serum

Question 8

describe the terms behind the “LOSS” findings on an x ray of osteoarthritis

Answer 8

Loss of joint space
Osteophytes
Sclerosis
Subchondral cysts

Question 9

4 types of inflammatory arthropathy

Answer 9

seropositive
seronegative
infectious
crystal deposition

Question 10

morning stiffness, improvement in symptoms with exercise - inflammatory or non-inflammatory?

Answer 10

inflammatory

Question 11

what can happen to the upper spine in RA if untreated

Answer 11

antlano-axial subluxation

cervical cord compression

Question 12

lung involvement in RA?

Answer 12

pleural effusions
interstitial fibrosis
pulmonary nodules

Question 13

what DAS score do patients have to have to be eligible for biological therapy

Answer 13

> 5.1

Question 14

name the 4 seronegative arthropathies?

Answer 14

ankylosing spondylitis
psoriatic arthritis
enteropathic arthritis
reactive arthritis

Question 15

common side effects of ankylosing spondylitis?

Answer 15

uveitis
aortitis
pulmonary fibrosis
amyloidosis

Question 16

what condition is almost always associated with systemic sclerosis

Answer 16

raynauds

Question 17

which areas of the body does polymyositis tend to affect

Answer 17

proximal areas symmetrically

Question 18

what kind of activities are difficult in polymyositis sufferers?

Answer 18

climbing stairs

Question 19

common comorbidities of polymyositis?

Answer 19

ILD (especially anti-Jo +ve patients)

dysphagia

Question 20

autoantibodies present in polymyositis

Answer 20

ANA
anti-Jo-1
anti-SRP

Question 21

management of polymyositis?

Answer 21

prednisolone (initially around 40mg) immunosuppression- methotrexate or azathioprine

Question 22

skin presentation of dermatomyositis?

Answer 22

heliotrope rash
v shaped rash over neck
gottron’s papules

Question 23

important conditions to rule out for fibromyalgia?

Answer 23

hypothyroidism
RA
SLE
polymyalgia rheumatica
autoimmune disorders

Question 24

what imaging can be done to detect giant cell arteritis

Answer 24

MR angiography

Question 25

treatment for large vessel vasculitis?

Answer 25

corticosteroids starting at 40-60mg

may add methrotrexate

Question 26

most important complication of microscopic polyangiitis

Answer 26

glomerulonephritis

Question 27

what mediates henoch schonlein purpura?

Answer 27

IgA

Question 28

what condition would you suspect in a small vessel vasculitis involving the GI tract, kidneys and joints

Answer 28

henoch schonlein purpura

Question 29

purpuric rash over the buttocks and lower limbs with vomiting and joint pain?

Answer 29

henoch schonlein purpura