CORTEXT: Rheumatology Flashcards
what does arthropathy mean?
disease of a joint
what does arthritis mean?
inflammation of the joint
what does arthralgia mean?
pain in the joint
most common type of non-inflammatory arthritis?
osteoarthritis
name the 5 seropositive arthritises?
RA lupus scleroderma vasculitis sjogren's
name the 4 seronegative arthritises?
ankylosing spondylitis
psoriatic arthritis
reactive arthritis
IBD arthritis
what is meant by a seropositive condition?
autoantibodies present in serum
describe the terms behind the “LOSS” findings on an x ray of osteoarthritis
Loss of joint space
Osteophytes
Sclerosis
Subchondral cysts
4 types of inflammatory arthropathy
seropositive
seronegative
infectious
crystal deposition
morning stiffness, improvement in symptoms with exercise - inflammatory or non-inflammatory?
inflammatory
what can happen to the upper spine in RA if untreated
antlano-axial subluxation
cervical cord compression
lung involvement in RA?
pleural effusions
interstitial fibrosis
pulmonary nodules
what DAS score do patients have to have to be eligible for biological therapy
> 5.1
name the 4 seronegative arthropathies?
ankylosing spondylitis
psoriatic arthritis
enteropathic arthritis
reactive arthritis
common side effects of ankylosing spondylitis?
uveitis
aortitis
pulmonary fibrosis
amyloidosis
what condition is almost always associated with systemic sclerosis
raynauds
which areas of the body does polymyositis tend to affect
proximal areas symmetrically
what kind of activities are difficult in polymyositis sufferers?
climbing stairs
common comorbidities of polymyositis?
ILD (especially anti-Jo +ve patients)
dysphagia
autoantibodies present in polymyositis
ANA
anti-Jo-1
anti-SRP
management of polymyositis?
prednisolone (initially around 40mg) immunosuppression- methotrexate or azathioprine
skin presentation of dermatomyositis?
heliotrope rash
v shaped rash over neck
gottron’s papules
important conditions to rule out for fibromyalgia?
hypothyroidism RA SLE polymyalgia rheumatica autoimmune disorders
what imaging can be done to detect giant cell arteritis
MR angiography
treatment for large vessel vasculitis?
corticosteroids starting at 40-60mg
may add methrotrexate
most important complication of microscopic polyangiitis
glomerulonephritis
what mediates henoch schonlein purpura?
IgA
what condition would you suspect in a small vessel vasculitis involving the GI tract, kidneys and joints
henoch schonlein purpura
purpuric rash over the buttocks and lower limbs with vomiting and joint pain?
henoch schonlein purpura
