Connective tissue Flashcards
overall connective tissue function:
structural/ metabolic support for other tissues (eg. epithelium)
connective tissue feature and consists of:
well vascularised (mostly)
cells, extracellular matrix (fibres + ground substance)
connective tissue all develop from:
embryonic mesenchymal cells
blast:
immature cell
cyte:
mature cell
cells either fixed and wondering:
resident and transient
list the 4 types of cells:
fibroblasts, adipocytes, chondroblasts and osteoblasts
list the 5 defence-function cells:
mast cell, macrophages, lymphocytes, plasma cells and eosinophils
fibroblast/cyte difference-
info/ function/ cell consists of:
blast:
most common cell, large, abundant cytoplasm processes, oval nucleus, lots of rER/ GA
quiescent (inactive) cyte: smaller, spindle shaped with elongated nucleus
synthesis of collagen, elastic, reticular fibres and extracellular material
WOUND REPAIR!
cell function/ features/ location: adipocytes
- fat storage, energy, insulation, also involvement in hormones/ growth factors
- eg. in loose connective tissue
- cytoplasm and flat nucleus forms rim around large lipid droplet
macrophage features/ function/ develop from:
- irregular shaped with small branched projections,
- destroys bacteria/ cellular debris (phagocytosis)
- developed from monocytes (WBC)
- fixed and wondering
mast cells: develop/ features, function
- develop in bone marrow, differentiate in connective tissue
- inflammatory and allergic response (granules contain histamine-allergy/ heparin-blood thinner)
- also kill bacteria
types of fibres in extracellular matrix:
collagen, reticular, elastic
types of ground substance and features:
fluid, semisolid, solid
water + complex carbs + glycoproteins
extracellular matrix function:
mechanical/ structural support for tissue, biochemical barrier -> regulate metabolic functions in surrounding cells
collagen fibres features/ composition:
- most abundant, closely packed and organised,
- flexible, high tensile strength
- collagen protein