CNS DRUGS - GENERAL ANESTHETICS Flashcards
Genetic disorder of susceptible individuals upon exposure to volatile anesthetics and succinylcholine
MALIGNANT HYPERTHERMIA
known to cause CORONARY STEAL SYNDROME, the preferential redistribution of blood from ischemic areas to non-ischemic areas,
ISOFLURANE
* ISO (I saw) you STEAL my heart! ISOFLURANE! CORONARY STEAL SYNDROME!!!
causes Renal insufficiency (due to Compound A formation)
SEVOFLURANE *yung V baliktarin mo, mukhang A. compound A!! Renal insufficiency!
ALL inhaled anesthetics have BRONCHODILATING properties except
DESFLURANE (and ISOFLURANE to a lesser extent) – can cause airway irritability and hence is unsuitable for induction
produces the MOST carbon monoxide out of all the inhaled anesthetics
Desflurane
Lowest potency (highest MAC) and least cardiotoxic among inhalational anesthetics
Nitrous oxide
Mnemonic for IV Anesthetics lifted from USMLE: the mighty King Proposes to Oprah:
Thiopental Midazolam, Ketamine, Propofol and Opioids
most reliable test to establish susceptibility to malignant hyperthermia
Caffeine-Halothane contracture test
“Milk of Amnesia”
PROPOFOL
Described as sweet smelling
SEVOFLURANE
antidote to Opioid analgesic (Fentanyl, morphine)
NALOXONE(DOC) / NALTREXONE
treatment of MALIGNANT HYPERTHERMIA
DANTROLENE
inhaled anes that can cause HEPATITIS
Halothane Hepatitis (immune mediated response characterized by eosinophilia)
used for DISSOCIATIVE ANESTHESIA (analgesia, amnesia and catatonia but with retained consciousness)
KETAMINE
causes EMERGENCE DELIRIUM
KETAMINE
IV anes that causes ADRENOCORTICAL SUPPRESSION
ETOMIDATE
unique amongst all inhaled anesthetics in that it requires a vaporizer because special heated and at normal room pressurized temperature, it would boil
DESFLURANE
IV anesthetic induction of choice
PROPOFOL
the lower the blood:gas partition coefficient, the ____ the rate of induction and recovery
the lower the blood:gas partition coefficient, the HIGHER the rate of induction and recovery
Inhaled anes contraindicated for patients with asthma and hyperreactive airways
DESFLURANE
Dissociative anesthesia seen in ketamine is characterized by ______ apparent in EEG
thalamocortical dissociation
inhaled anesthetic with lowest partition coefficient
nitrous oxide
inhaled anesthetic that has the highest MAC
Nitrous oxide
only inhaled anesthetic that INCREASES cerebral blood flow and hence INCREASE ICP due to activation of sympathetic nervous system
Nitrous oxide
