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PHARMACOLOGY > ANTIBIOTICS - ANTIPROTOZOAL > Flashcards

ANTIBIOTICS - ANTIPROTOZOAL Flashcards

1
Q

examples of TISSUE SCHIZONTICIDES (kill schizonts in the liver)

A

primaquine, atovaquone

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2
Q

examples of BLOOD SCHIZONTICIDES

A

chloroquine, quinine mefloquine, atovaquone, pyrimethamine, doxycycline, halofantrine, artemisinin

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3
Q

example of GAMETOCIDES

A

primaquine

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4
Q

examples of SPORONTICIDES (prevent sporogony and multiplication in the mosquito)

A

proguanil, pyrimethamine

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5
Q

Side effect include Cinchonism (headache, tinnitus, vertigo), Hemolysis in G6PD deficiency, Blackwater fever

A

QUININE

QUINIDINE GLUCONATE

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6
Q

DOC for malaria in pregnant patients

A

Quinine

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7
Q
  • severe complication of P. falciparum malaria
  • characterized by intravascular hemolysis, massive hemoglobinuria and acute renal failure
A

Blackwater fever

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8
Q

radical cure of P. vivax, P. ovale

Terminal prophylaxis (vivax, ovale)

A

PRIMAQUINE

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9
Q

Treatment and chemoprophylaxis (chloroquine-resistant P.falciparum) - all stages

A

ATOVAQUONE-PROGUANIL

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10
Q

Common side effect is a headache without organic lesion that is Pseudotumor cerebri.

A

Doxycycline

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11
Q

Forms toxic free radicals in malarial food vacuole. Blood schizonticide.

A

ARTEMISININ

ARTESUNATE, ARTEMETHER, DIHYDROARTEMISININ

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12
Q

the drug of choice for uncomplicated falciparum malaria in the Philippines

A

Artemether-Lumefantrine (Co-Artem)

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13
Q
A
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14
Q

DOC for Chloroquine sensitive P. falciparum

A

Chloroquine

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15
Q

DOC for P. vivax and P. ovale

A

Chloroquine then Primaquine

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16
Q

examples of TISSUE AMEBICIDES (act on organisms in the bowel wall and the liver)

A

chloroquine, emetines, metronidazole, tinidazole

17
Q

examples of LUMINAL AMEBICIDES (act only in the lumen of the bowel)

A

diloxanide furoate, iodoquinol, paromomycin

18
Q

Asymptomatic cyst carriers of E. histolytica (drug of choice)

A

DILOXANIDE FUROATE

19
Q

used for Severe intestinal and extraintestinal amebiasis (drug of choice), Trichomoniasis, Giardiasis, Bacterial vaginosis, Anaerobic infections (B. fragilis, C. difficile), Peptic ulcer disease

A

Metronidazole

20
Q

DOC for Cryptosporidiosis

A

NITAZOXANIDE

21
Q

Prophylaxis and treatment of pneumocystosis (drug of choice), Prophylaxis (T. gondii, I. belli)

A

CO-TRIMOXAZOLE

22
Q

Prophylaxis and treatment of Toxoplasmosis (drug of choice)

A

SULFADIAZINE-PYRIMETHAMINE

23
Q

Advanced West African sleeping sickness (drug of choice)

A

EFLORNITHINE

24
Q

African sleeping sickness (drug of choice)

A

MELARSOPROL

25
Q

Chagas disease (drug of choice),

A

NIFURTIMOX

26
Q

Leishmaniasis (drug of choice except in India)

A

SODIUM STIBOGLUCONATE

27
Q

Whipworm infections (drug of choice),

A

MEBENDAZOLE

28
Q

Trichinosis (drug of choice),

A

THIABENDAZOLE

29
Q

Filariasis (drug of choice), Eye worm disease (drug of choice),

A

DIETHYLCARBAMAZINE

31
Q

May cause Mazzotti reaction when used for onchocerciasis

A

DIETHYLCARBAMAZINE

32
Q

Strongyloidiasis (drug of choice),

A

IVERMECTIN

33
Q

can cause Mazzoti reaction (fever, headache, dizziness, rashes, pruritus, tachycardia, hypotension, pain in joints, muscles and lymph glands),

A

IVERMECTIN

34
Q

Ascaris, Hookworm and Pinworm infections (drug of choice),

A

PYRANTEL PAMOATE

35
Q

Ascariasis, Hookworm, Pinworm, Hydatid disease (drug of choice), Whipworm infections, Cutaneous & Visceral Larva migrans, Cysticercosis (larval stages of T. solium), Angiostrongylus cantonensis, Capillaria philippinensis

A

ALBENDAZOLE

36
Q

Drug of choice for trematodes / flukes (Schistosoma, Paragonimus, Clonorchis, Opisthorchis, Fasciolopsis, Heterophyes) and cestodes / tapeworms (Taenia, Diphyllobothrium, Hymenolepsis)

A

PRAZIQUANTEL

37
Q

Prazaquantel is the DOC of flukes except Fasciola hepatica. What is its DOC?

A

bithionol or triclabendazole

38
Q

Ivermectin is the DOC for ____ and _____

A

STRONGYLOIDES AND ONCOCERCA VOLVULUS

PHARMACOLOGY (31 decks)

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