CARDIO - ANGINA PECTORIS

Question 1

What is the antidote for cyanide poisoning?

Answer 1

Lilly Cyanide Kit: inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate

Question 2

Treatment for Methemoglobinemia?

Answer 2

Low dose Methylene blue

Question 3

DRUGS USED IN ANGINA PECTORIS

Answer 3

Question 4

MOA of Short-acting nitrates : NITROGLYCERIN, ISOSORBIDE DINITRATE [C], ISOSORBIDE MONONITRATE [C]

Answer 4

Releases nitric oxide (NO), increases cGMP (cyclic guanosine monophosphate), and relaxes smooth muscle, especially vascular

Question 5

used for cyanide poisoning

Answer 5

AMYL NITRITE

* Releases nitric oxide (NO), increases cGMP (cyclic guanosine monophosphate), and relaxes smooth muscle, especially vascular

Question 6

Dangerous hypotension with PDE inhibitors such as Sildenafil

Answer 6

NITROGLYCERIN, ISOSORBIDE DINITRATE [C], ISOSORBIDE MONONITRATE [C]

Question 7

DOC for Prinzmetal Angina

Answer 7

DILTIAZEM (Non-dihydropyridine calcium channel blocker)

Question 8

MOA: In funny Na current in SA node, decreases hyperpolarization-induces inward pacemaker current → decrease HR and cardiac work

Answer 8

IVABRADINE

Question 9

Why do patients taking nitrates usually experience throbbing headaches?

Answer 9

due to meningeal blood vessel vasodilation

Question 10

Part of the Lilly Cyanide Kit as short acting nitrite to cause oxidation of Fe methemoglobin

Answer 10

AMYL NITRITE