CARDIO - ANGINA PECTORIS Flashcards
What is the antidote for cyanide poisoning?
Lilly Cyanide Kit: inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate
Treatment for Methemoglobinemia?
Low dose Methylene blue
DRUGS USED IN ANGINA PECTORIS
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MOA of Short-acting nitrates : NITROGLYCERIN, ISOSORBIDE DINITRATE [C], ISOSORBIDE MONONITRATE [C]
Releases nitric oxide (NO), increases cGMP (cyclic guanosine monophosphate), and relaxes smooth muscle, especially vascular
used for cyanide poisoning
AMYL NITRITE
* Releases nitric oxide (NO), increases cGMP (cyclic guanosine monophosphate), and relaxes smooth muscle, especially vascular
Dangerous hypotension with PDE inhibitors such as Sildenafil
NITROGLYCERIN, ISOSORBIDE DINITRATE [C], ISOSORBIDE MONONITRATE [C]
DOC for Prinzmetal Angina
DILTIAZEM (Non-dihydropyridine calcium channel blocker)
MOA: In funny Na current in SA node, decreases hyperpolarization-induces inward pacemaker current → decrease HR and cardiac work
IVABRADINE
Why do patients taking nitrates usually experience throbbing headaches?
due to meningeal blood vessel vasodilation
Part of the Lilly Cyanide Kit as short acting nitrite to cause oxidation of Fe methemoglobin
AMYL NITRITE