Chapter 21 - Pesticides Flashcards
Human male reproductive effects have been demonstrated after exposure to…
A. Permethrin
B. Chlordecone
C. Piperonyl butoxide
D. None of the above
B. Chlordecone
An adjunct in the treatment of organophorus poisoning is…
A. Morphine
B. Aminophylline
C. Prochlorperazine
D. None of the above
D. None of the above
Which of the following is the most commonly used rodenticide?
A. Strychnine
B. Alpha-napthyltiourea
C. Rotenone
D. Anticoagulants
D. Anticoagulants
Which of the following is a plant growth regulator?
A. Gibberellic acid
B. Glyphosate
C. Simazine
D. Asulam
A. Gibberellic acid
Many of the organochlorine insecticides are no longer in use because of…
A. Environmental persistence
B. Bioaccumulation
C. Cancer in lab animals
D. All of the above
D. All of the above
Piperonyl butoxide…
A. Is synergistic with pyrethins
B. Has additive activity to pyrethrins
C. Is a renal toxicant
D. In lab animals, initial induction of P450 is followed by inhibition
A. Is synergistic with pyrethins
Which of the following has caused thyroid carcinoma in lab animals?
A. Warfarin
B. Zineb
C. Chlordecone
D. Dieldrin
B. Zineb
The cause of death in acute organophosphate poisoning is usually…
A. Respiratory failure
B. Cardiac arrhythmia
C. Status epilepticus
D. Hypothermia
A. Respiratory failure
All of the following are true of individuals with a genetic predisposition for an abnormal plasma cholinesterase except…
A. They have prolonged paralysis after succinylcholine
B. They have a normal response to curare
C. They are more susceptible to organophosphates
D. Dibucaine number is a measure of activity
C. They are more susceptible to organophosphates
The least toxic agent in terms of oral LD50 is…
A. Parathion
B. Alpha-naphthylthiourea
C. Aldicarb
D. Resmethin
D. Resmethin
There have been conflicting studies about the relationship between DDE serum levels and…
A. Breast cancer
B. Osteosarcoma
C. Dementia
D. Acute leukemia
A. Breast cancer
All of the following organochlorine pesticides are still in use in the US except…
A. Dicofol
B. Chlodecone
C. Endosulfan
D. Lindane
B. Chlodecone
The advantage of 2-PAM over atropine in the treatment of organophosphate poisoning is…
A. It is helpful in arrhythmias
B. It suppresses seizures
C. It acts at the neuromuscular junction
D. It prevents delayed neuropathy
C. It acts at the neuromuscular junction
Poisoning with chlordecone has been treated with…
A. Cholestyramine
B. Propranolol
C. 2-PAM
D. None of the above
A. Cholestyramine
The mechanism of action of sodium fluoroacetate is…
A. Inhibition of glucose-6-phosphate dehydrogenase
B. Inhibition of cytochrome oxidase
C. Inhibition of aconitase
D. Inhibition of DNA polymerase
C. Inhibition of aconitase
The acute toxicity of which of the following compounds has been proposed to be due to the presence of surfactant in their formulations?
A. Captan and folpat
B. Glyphosate and glufosinate
C. Atrazine and simazine
D. Alachlor and metolachlor
B. Glyphosate and glufosinate
The primary toxicity of elemental sulfur exposure in humans is…
A. Dermatitis
B. Skin cancer
C. Immune supression
D. Polycythemia
A. Dermatitis
All of the following are true of DDT except…
A. Convulsions can occur in severe poisoning
B. The liver is the target organ
C. An early symptom of exposure in humans is hyperesthesia
D. It is a cyclohexane derivative
D. It is a cyclohexane derivative
The presence of dimethylphosphate in urine is an indication of exposure to…
A. Propoxur
B. Dichlorvos
C. Fenvalerate
D. Heptachlor
B. Dichlorvos
Paraquat…
A. Is a rodenticide
B. Interferes with calcium channels
C. Is well absorbed orally
D. Is transported into the lung
D. Is transported into the lung
Which of the following is true of diaquat?
A. It is bone marrow toxic
B. It causes cataracts in animals
C. It is teratogenic
D. It accumulates in the liver
B. It causes cataracts in animals
2,4, D…
A. Is called Agent Orange
B. Is chemically similar to auxin
C. Has been formulated to contain up to 70% TCDD
D. Is a chloroacetanilide herbacide
B. Is chemically similar to auxin
DEET…
A. Is cardiotoxic
B. Inhibits photosynthesis
C. Is widely used and has a good safety record
D. Has a high incidence of dermatitis
C. Is widely used and has a good safety record
All of the following are true of imidocloprid except…
A. It is structurally similar to nicotine
B. It has selective toxicity for insects over mammals
C. It can be toxic to birds
D. It has been banned worldwide
D. It has been banned worldwide
Lepidopteran is an example of a…
A. Preemergent herbicide
B. Phermone
C. Recently introduced pesticide
D. Banned fungicide
B. Phermone
A mechanism of action for organotin fungicide is…
A. Stimulation of apoptosis
B. Inhibition of succinate dehydrogenase
C. Binding of cytochrome B1
D. Binding to ATP synthase
D. Binding to ATP synthase
The toxin from Bacillus thuringiensis is called…
A. Delta-endotoxin
B. Bufotalin
C. Bactrachotoxin
D. Ciguatoxin
A. Delta-endotoxin
The mechanism of action of triazine herbacides is…
A. Activation of auxin receptor
B. Inhibition of photosynthetic electron transport
C. Inhibition of fatty acid synthesis
D. Inhibition of microtubule assembly
B. Inhibition of photosynthetic electron transport
Which of the following is true of an uncoupler of mitochondrial respiration?
A. Increase in pH of cytoplasm
B. Carboxyhemoglobin increases in red cells
C. Oxygen consumption increases and ATP production decreases
D. None of the above
C. Oxygen consumption increases and ATP production decreases
All of the following are symptoms of organophosphorus insecticide poisoning except…
A. Muscle twitching
B. Diarrhea
C. Mydriasis
D. Vomiting
C. Mydriasis
Oxine therapy 24 hrs after exposure to methyoxychlor is useless because…
A. Of the process of aging
B. Irreversible damage has occurred by 24 hrs
C. It takes at least 48 hrs for the active metabolite of methoxychlor to cause toxicity
D. Oxines are not indicated in organophosphorus insecticide toxicity
D. Oxines are not indicated in organophosphorus insecticide toxicity