Chap 10: Endocrine System (Transes) Flashcards
Composed of endocrine glands and specialized
endocrine cells throughout the body
ENDOCRINE SYSTEM
Dissolves in water
WATER SOLUBLE
They have a positive and negative end
WATER SOLUBLE
They dissolve in water because they have polar molecules
WATER SOLUBLE
Endocrine glands and cells secrete minute amounts of
chemical messengers called
hormones
Insulin, Adrenaline, Glucagon
WATER SOLUBLE
Cannot pass
through the cell
membrane
WATER SOLUBLE
They do not enter
cell instead they
bind to receptors
outside the cell
membrane
WATER SOLUBLE
Need for binding proteins: No
WATER SOLUBLE
Half life of WATER SOLUBLE
Shorter
More easily
degraded (by
enzymes or
pathogens)
WATER SOLUBLE
Dissolves in fats
LIPID SOLUBLE
They dissolve in
lipids because
they have
nonpolar
molecules
LIPID SOLUBLE
They do not have
a positive and
negative charge
LIPID SOLUBLE
Can easily pass
through the cell
membrane
LIPID SOLUBLE
Thyroid, cortisol,
estrogen,
testosterone
LIPID SOLUBLE
Protected by
binding proteins
(from breaking
down)
LIPID SOLUBLE
Half life of LIPID SOLUBLE
Longer (in the
bloodstream)
Need for binding proteins: Yes
LIPID SOLUBLE
The release of hormone is tightly regulated by three
main types of stimuli:
o Humoral
o Neural
o Hormonal
Hormone release in
response to
changes in blood
vessels of ions or
nutrients
Humoral Stimuli
Hormone release
stimulated by nerve
impulses (from the
nervous system)
Neural stimuli
body fluids like the blood
Humoral
where hormones released by
the hypothalamus that stimulates
the Pituitary gland which
then stimulates thyroid gland,
gonads, etc.
Hypothalamic Pituitary Axis (HPA)
Hormone release
regulated by other
hormones
Hormonal Stimuli
AKA PITUITARY GLAND
Hypophysis
Controlled by hypothalamus
PITUITARY GLAND
Master gland
PITUITARY GLAND
75% of the gland
Anterior pituitary
Adenohypophysis
ANTERIOR PITUITARY GLAND
Pharyngeal
Epithelium
ANTERIOR PITUITARY GLAND
Releases or inhibits hormones
ANTERIOR PITUITARY GLAND
Production of Milk
Prolactin
Increased
prolactin in
female
Amenorrhea
Increased
prolactin in
male
Erectile
dysfunction
Growth of
long bones
and soft
tissues
Growth Hormone
Increased GH
at childhood
Gigantism
Increased GH
at adult life
Acromegaly