Ch 4 Test Yourself Flashcards

1
Q

List three fluid compartments in the body

A

Intracellular, interstitial, intravascular

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2
Q

What is an electrolyte?

A

A charged particle (an anion or a cation) capable of conducting an electric current in solution

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3
Q

Give specific examples of both cation and anions

A

Cations:
* Potassium (K+)
* Magnesium (Mg2+)
* Calcium (Ca2+)
* Sodium (Na+)
Anions:
* Sulfate (SO42−)
* Hydrogen phosphate (HPO4 2−)
* Chloride (Cl−)
* Bicarbonate (HCO3−)

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4
Q

Which electrolytes are normally more concentrated outside the cell and which ones are more concentrated inside the cell?

A

Potassium is more concentrated inside the cell, sodium is more concentrated outside the cell

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5
Q

What is the relationship between solutes and osmolality?

A

Osmolality is a measurement of the concentration of solute in fluid; as the concentration of solute increases, osmolality also increases

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6
Q

Give specific examples of solutes in the body

A

Soluble proteins, phospholipids, cholesterol, triglycerides, sulfate, hydrogen phosphate, chloride, bicarbonate, magnesium, calcium, potassium, sodium

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7
Q

Why do changes in osmolality cause fluid to move from one compartment to another?

A

Water moves freely between fluid compartments based on changes in osmolality; fluid moves toward the compartment with the highest concentration of solutes

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8
Q

Give two examples of conditions that result from fluid shifts

A

Pulmonary edema, cutaneous edema

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9
Q

How do changes in the osmolality of body fluids affect an animal’s desire to drink?

A

An increase in osmolality stimulates the desire to drink and the release of antidiuretic hormone (ADH)

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10
Q

What is diffusion? Is it an active or a passive membrane process?

A

Diffusion is the passive movement of solute down a concentration gradient

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11
Q

What molecules are more likely to diffuse into a cell? What three principles are involved?

A

Molecules: Very small molecules (e.g., water), lipid-soluble molecules (e.g., alcohol, steroids), dissolved gases (e.g., O2, CO2)
Principles:
* Molecular size
* Lipid solubility
* Molecular charge

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12
Q

How is facilitated diffusion different from simple diffusion?

A

Facilitated diffusion requires the assistance of an integral protein or carrier protein; the number of available carrier proteins limits the rate of facilitated diffusion

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13
Q

What effect does a hypotonic solution have on a cell?

A

Water flows into the cell causing it to swell and possibly burst

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14
Q

What is the relationship between hydrostatic pressure and filtration?

A

Filtration is based on a pressure gradient; liquids are pushed through a membrane if the pressure on one side is greater than the other

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15
Q

What is another name for hydrostatic pressure in the body?

A

Blood pressure

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16
Q

What defines a passive membrane process?

A

A passive membrane process is one that does not require energy (ATP)

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17
Q

When is a membrane process considered active?

A

When the process requires energy

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18
Q

How do electrolytes enter the cell?

A

Via active transport

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19
Q

What is the difference between a symport and an antiport system?

A

Symport moves substances in the same direction; antiport moves substances in opposite directions

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20
Q

Describe how sodium and potassium enter and exit the cell

A

Potassium tends to diffuse out, sodium diffuses in; the cell must actively pump potassium in and sodium out

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21
Q

Describe the three types of endocytosis

A

Phagocytosis (solid material engulfing), pinocytosis (liquid engulfing), receptor-mediated endocytosis (specific ligands engulfing)

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22
Q

What is the difference between excretion and secretion?

A

Excretion is waste removal; secretion is movement of manufactured molecules; both are examples of exocytosis

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23
Q

What are the principal ions involved in maintaining a cell’s resting membrane potential?

A

Sodium and potassium

24
Q

Is there normally a higher concentration of sodium inside or outside the cell?

A

Outside the cell

25
Where is there a higher concentration of potassium?
Inside the cell
26
What are the two major periods that comprise the life cycle of the cell?
Interphase and mitotic phase
27
Is interphase a time when the cell is resting? Why or why not?
No, interphase is a period of intense metabolic activity
28
What are the four stages of the mitotic phase?
Prophase, metaphase, anaphase, telophase
29
What happens in prophase?
Chromatin coils into chromosomes, cytoplasm becomes viscous, and a mitotic spindle forms
30
What happens in metaphase?
Chromosomes line up at the equator of the spindle, forming the metaphase plate
31
What happens in anaphase?
Centromeres split, chromatids are pulled apart, and the cell elongates
32
What happens in telophase?
Chromosomes unwind, nuclear envelopes form, and cytokinesis begins
33
What two major molecular components make up chromatin?
DNA and histone proteins
34
Why is it important for chromatin to supercoil and form discrete chromosomes before cell division?
To enable equitable division of genetic material without tangling or breaking
35
Why is protein and enzyme synthesis more likely to occur during interphase?
Chromosomes unwind, allowing access to DNA for transcription
36
What three factors play a role in the control of cell division?
Contact inhibition, growth-inhibiting substances, checkpoints during cell division
37
What is the genetic basis of cellular differentiation?
The position of genes in chromosomes determines gene accessibility for transcription
38
Of the thousands of different proteins that a cell could make, how many does it actually produce?
A few hundred kinds due to different cell functions
39
Where does protein synthesis begin?
In the nucleus
40
What is a nucleotide and how is it structured?
A nucleotide consists of a sugar, phosphate group, and nitrogenous base
41
Compare and contrast the structures of DNA and RNA
DNA has thymine; RNA has uracil; DNA is double-stranded; RNA is single-stranded
42
What are the nucleotides found in DNA?
Adenine (A), cytosine (C), guanine (G), thymine (T)
43
What are the nucleotides found in RNA?
Adenine (A), cytosine (C), guanine (G), uracil (U)
44
What is the term for mRNA formation?
Transcription
45
What are codons and what role do they play in transcription?
A codon is a set of three nucleotides in mRNA that specifies an amino acid or signals the end of synthesis
46
Can you describe the events that occur in translation?
Translation is the process of making protein from mRNA with the aid of ribosomes in the cytoplasm
47
What is the process of messenger RNA (mRNA) formation called?
Transcription ## Footnote Transcription occurs in the nucleus.
48
What is a codon?
A set of three adjacent nucleotides in an mRNA molecule ## Footnote Codons specify the incorporation of an amino acid or signal the end of peptide synthesis.
49
What role do codons play in transcription?
They specify the incorporation of an amino acid into a peptide or signal the end of peptide synthesis.
50
What is the process of making protein from mRNA called?
Translation ## Footnote Translation occurs in the cytoplasm with the aid of ribosomes.
51
Where does translation occur in the cell?
In the cytoplasm ## Footnote Ribosomes facilitate the translation process.
52
What do ribosomes do during translation?
They attach to mRNA and read the genetic sequence.
53
What is the function of transfer RNA (tRNA) in translation?
To bond to mRNA and bring amino acids for protein synthesis.
54
Fill in the blank: The 'reading' process in translation involves the bonding of a specific _______ on the tRNA to a complimentary codon on the mRNA.
anticodon
55
What forms on the ribosome during translation?
A polypeptide chain ## Footnote This chain forms as amino acids bond together.
56
What happens to the polypeptide chain once it reaches its required length?
It disconnects from the ribosomal docking station.
57
When does DNA replication occur in the cell cycle?
During the synthetic (S) phase of interphase.