Cell Cycle class notes Flashcards
cyclins: proteins made by the cell, for the cell
doesn’t use .. system
moderates the ..
.. dependent
regulates passage of … stages: … bind with cyclins to pass between cell cycle stages
monitoring progression through cell cycle
endomembrane; cell cycle; concentration; cell cycle; cyclin dependent kinases
steps of cell cycle:
G1, G2, S –> …
M phase –> … and …
interphase; mitosis; cytokinesis
multinucleated … cells –> undergo mitosis, but this is not followed by …
these only undergo ..
more … solves the problem of …, because it provides more … that the enlarging of the cell is diminishing. as such .. are more …
muscle; cytokinesis; mitosis; nuclei; surface area to volume ratio; surface area; larger muscle cells; efficient
examples of cells that don’t undergo division: ..
these go into … –> no .., they don’t even go into …
neurons; G0; division; interphase
… arm of chromosome has more strain during crossing over–> the genes on this arm are more likely to … in the offspring –> …/ … genes
short; appear together; linkage; linked
… between genes is a factor in crossing over
… involved in crossing over
location; homologous pairs
cancer treatments:
chemotherapy: involves ../…, etc to deliver … that target .. –> downside is that it targets … (whcih effects …) as well as .. cells, and .. of … system
IV; stent; chemicals; dividing cells; skin cells; hair; blood; lining; digestive
cancer treatments:
radiation: focusing a … of a .. towards … to … them
can lead to …
beam; radioactive substance; rapidly dividing cells; kill; radiation sickness
cancer treatments:
targeting … and .. to restore their proper function/ .. them depending on what the target is (… therapy, e.g. …)
ras; p53; disable; target; Gleevec
G1: cells … and synthesize .. needed for …, regular .. function
grow; proteins; DNA replication; metabolic
S: major function is .., using enzymes to … After this phase, each chromosome has …
DNA replication; copy the DNA; 2 chromatids
G2: another period of .., more … are made, … grow and divide, cells continue their …
growth; proteins; organelles; normal function
(mitosis) prophase: chromosomes …, … forms at edges of cells (made up of …)
condense; mitotic spindle; microtubules
(mitosis) prometaphase: … is broken down, chromosomes beginning to …, …
nuclear envelope; line up; spindles attaching
(mitosis) metaphase: …
chromosomes line up
(mitosis) anaphase:
sister chromatids separate
(mitosis) telophase: … reforms, two … present with individual … in them
nuclear envelope; nuclear envelopes; chromatids
(mitosis) cytokinesis: division of
cytoplasm
kinetochore: complex of .. associated with .. during cell division, this is where … of … attach
… produces the spindls
kinetochore .. of the spindle
proteins; centromere; microtubules; spindle; centrosome; shortens length
proto-oncogene examples: …, …
ras; EGFR
… cells undergo mitosis. … undergo meiosis
somatic; sex
meiosis I: … separating, … occurs
meiosis II: … separating, relates more closely to …, … occurs
homologues; interkinesis; sister chromatids; mitosis; cytokinesis
chiamsa: where homologous pairs … and where … occurs
link together; crossing over
differentiation: difference in … from ..
gene expression; precursor cell
cyclins are an … regulation of the cell cycle
internal
after the embryonic stage, (… days within humans), the cells can no longer … into alll … …, not …, occurs after this stage
4; differentiate; types of cells; growth; differentiation
no differentiation of cells occurs during
fetal development
parthenogenesis: female produces egg that develops without being ., always …, occurs in … (e.g. komodo dragons) and …
fertilized; haploid; lizards; male bees